Ignite Creation Date:
2024-10-25 @ 7:48 PM
Last Modification Date:
2024-10-26 @ 3:43 PM
Study NCT ID:
NCT06657209
Status:
NOT_YET_RECRUITING
Last Update Posted:
None
First Post:
2024-10-18
Brief Title:
Normal-weight Diabetes Adipocyte-directed Therapy with Pioglitazone or Tirzepatide
Sponsor:
None
Organization:
None
Study Overview
Official Title:
Normal-weight Diabetes Adipocyte-directed Therapy with Pioglitazone or Tirzepatide
Status:
NOT_YET_RECRUITING
Status Verified Date:
2024-10
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
No
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
This study is to investigate how adipocyte fat cell function and fat distribution differ between individuals with normal-weight type 2 diabetes NWD and normal-weight controls without diabetes NWC The study will assess whether adipocyte-directed therapies specifically pioglitazone and tirzepatide can improve insulin resistance adipocyte function and fat distribution in individuals with NWD By analyzing the biological mechanisms underlying adipocyte dysfunction the study aims to provide insights into novel treatment strategies for improving metabolic health in normal-weight individuals with type 2 diabetes
Detailed Description:
The investigators aim to learn how adipocyte dysfunction and disordered fat distribution contribute to the development of type 2 diabetes in normal-weight individuals The investigators hope to determine whether adipocyte-directed therapies such as pioglitazone and tirzepatide can improve insulin sensitivity fat distribution and metabolic health in this population This study is important because most diabetes research focuses on overweight or obese individuals and very little is known about how diabetes affects those with normal body weight Understanding the unique biology of normal-weight diabetes could lead to more personalized and effective treatment strategies filling a gap in diabetes care for a group that can be overlooked in clinical research
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None