Ignite Creation Date:
2024-10-25 @ 7:48 PM
Last Modification Date:
2024-10-26 @ 3:42 PM
Study NCT ID:
NCT06643026
Status:
NOT_YET_RECRUITING
Last Update Posted:
None
First Post:
2024-10-14
Brief Title:
Sensory Evaluation of Taste and Smell in Oncology
Sponsor:
None
Organization:
None
Study Overview
Official Title:
Sensory Evaluation of Taste and Smell in Oncology
Status:
NOT_YET_RECRUITING
Status Verified Date:
2024-10
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
No
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
SENSEO
Brief Summary:
Nutritional status is a major issue in the management of cancer patients Forty to 60 of patients are undernourished at diagnosis This undernutrition has a direct impact on patients health and quality of life with a reduction in survival associated with an increase in the risk of toxicity from anti-cancer treatments chemotherapy radiotherapy surgery the risk of infection and the risk of hospitalization Thus it is estimated that 10-20 of cancer patients die from the consequences of their undernutrition rather than from the tumor itself Muscaritoli et al 2021
It is therefore recommended to systematically implement a multimodal nutritional intervention in cancer patients recommendations of the learned societies ESPEN ESMO and ASCO combining nutritional support oral andor enteral andor parenteral with physical exercise Muscaritoli et al 2021 However despite the systematic provision of dietary management the effectiveness of nutritional interventions varies from patient to patient in terms of nutritional status quality of life and overall survival Cintoni et al 2023
Among the factors impacting patient compliance with dietary measures and their efficacy sensory alterations occurring under chemotherapy potentially have a major impact Drareni et al 2019
Indeed the vast majority of patients describe an alteration in tastes and smells after starting chemotherapy treatment However few studies have focused on the specific parameters associated with these alterations The aim of this study is to prospectively assess changes in sensory perceptions and eating habits in patients undergoing chemotherapy for digestive cancer at the start of treatment and after the first cycle of chemotherapy and to correlate these alterations with patients nutritional profile and clinical course
It is therefore recommended to systematically implement a multimodal nutritional intervention in cancer patients recommendations of the learned societies ESPEN ESMO and ASCO combining nutritional support oral andor enteral andor parenteral with physical exercise Muscaritoli et al 2021 However despite the systematic provision of dietary management the effectiveness of nutritional interventions varies from patient to patient in terms of nutritional status quality of life and overall survival Cintoni et al 2023
Among the factors impacting patient compliance with dietary measures and their efficacy sensory alterations occurring under chemotherapy potentially have a major impact Drareni et al 2019
Indeed the vast majority of patients describe an alteration in tastes and smells after starting chemotherapy treatment However few studies have focused on the specific parameters associated with these alterations The aim of this study is to prospectively assess changes in sensory perceptions and eating habits in patients undergoing chemotherapy for digestive cancer at the start of treatment and after the first cycle of chemotherapy and to correlate these alterations with patients nutritional profile and clinical course
Detailed Description:
None
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None