Ignite Creation Date:
2024-07-17 @ 12:07 PM
Last Modification Date:
2024-10-26 @ 3:34 PM
Study NCT ID:
NCT06498778
Status:
COMPLETED
Last Update Posted:
2024-07-12
First Post:
2024-06-29
Brief Title:
Etiology and Prognosis of sICH Based on Hemorrhage Location
Sponsor:
Jinling Hospital China
Organization:
Jinling Hospital China
Study Overview
Official Title:
Prediction of Etiology and Prognosis Based on Hematoma Location of Spontaneous Intracerebral Hemorrhage
Status:
COMPLETED
Status Verified Date:
2024-07
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
The investigators retrospectively collected participants with spontaneous cerebral hemorrhagesICH from January 2015 to December 2019 for training and internal validation Clinical and imaging data were collected Modified Rankin Scale mRS scores were determined good outcome as mRS 0-2 poor outcome as mRS 3-6 The location features of sICH were extracted by symptom mapping Noncontrast computed tomography images of patients and hematoma masks were registered with standard human brain templates to identify specific affected brain regions Then a probability map of hemorrhage for different causes and prognosis is generated PyRadiomics was used to extract the radiomic features integrate radiomic and clinical features into multiple logistic regression models and develop and validate optimal etiological and prognostic models Further tests were performed in an independent cohort The area under the working characteristic curve AUC sensibility specificity were used to evaluate the reliability of the model
Detailed Description:
None
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None