Ignite Creation Date:
2024-07-17 @ 12:06 PM
Last Modification Date:
2024-10-26 @ 3:33 PM
Study NCT ID:
NCT06473337
Status:
COMPLETED
Last Update Posted:
2024-06-25
First Post:
2024-06-04
Brief Title:
Vitamin D Deficiency as Independent Predictor for Plaque Vulnerability
Sponsor:
Medical University of Vienna
Organization:
Medical University of Vienna
Study Overview
Official Title:
Vitamin D Deficiency as Independent Predictor for Plaque Vulnerability and All-cause Mortality in Patients With Symptomatic Carotid Artery Stenosis
Status:
COMPLETED
Status Verified Date:
2024-06
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
Role of vitamin D in cardiovascular disease is controversial Here the investigators aimed to investigate the association of vitamin D deficiency and carotid plaque morphology as well as outcome of participants with high-grade carotid artery stenosis undergoing carotid endarterectomy
332 consecutive participants undergoing carotid endarterectomy for symptomatic or asymptomatic carotid artery stenosis were prospectively included in the study and vitamin D levels were determined prior to surgery using chemiluminescence-immunoassay
332 consecutive participants undergoing carotid endarterectomy for symptomatic or asymptomatic carotid artery stenosis were prospectively included in the study and vitamin D levels were determined prior to surgery using chemiluminescence-immunoassay
Detailed Description:
Role of vitamin D in cardiovascular disease is controversial Here the investigators aimed to investigate the association of vitamin D deficiency and carotid plaque morphology as well as outcome of participants with high-grade carotid artery stenosis undergoing carotid endarterectomy
332 consecutive participants undergoing carotid endarterectomy for symptomatic or asymptomatic carotid artery stenosis were prospectively included in the study and vitamin D levels were determined prior to surgery using chemiluminescence-immunoassay
There is insufficient data on cardiovascular outcome in participants with CAS and vitamin D deficiency Vitamin D would be an easily modifiable factor
Primary goal was to investigate the influence of vitamin D levels on plaque vulnerability major adverse cardiovascular events MACE and all-cause mortality in patients with carotid artery disease undergoing carotid endarterectomy
332 consecutive participants undergoing carotid endarterectomy for symptomatic or asymptomatic carotid artery stenosis were prospectively included in the study and vitamin D levels were determined prior to surgery using chemiluminescence-immunoassay
There is insufficient data on cardiovascular outcome in participants with CAS and vitamin D deficiency Vitamin D would be an easily modifiable factor
Primary goal was to investigate the influence of vitamin D levels on plaque vulnerability major adverse cardiovascular events MACE and all-cause mortality in patients with carotid artery disease undergoing carotid endarterectomy
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None