Ignite Creation Date:
2024-07-17 @ 12:01 PM
Last Modification Date:
2024-10-26 @ 3:33 PM
Study NCT ID:
NCT06480305
Status:
RECRUITING
Last Update Posted:
2024-06-28
First Post:
2024-06-05
Brief Title:
Impact of Evening Snacks and Pre-Breakfast Intake on Sleep Heart Rate Variability and Stress Markers in Healthy Males
Sponsor:
Riphah International University
Organization:
Riphah International University
Study Overview
Official Title:
Effect Of Post Dinner Snack and Pre-Breakfast Consumption on Sleep Quality Heart Rate Variability Temperature Interleukin-6 And Cortisol Levels in Healthy Males
Status:
RECRUITING
Status Verified Date:
2024-08
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
The body has a natural 24-hour rhythm This rhythm affects factors like body temperature sleep and Heart Rate Variability HRV Dietary choices influence these physiological processes of the body Poor sleep quality can increase stress and raise levels of a hormone called cortisol affecting our heart and insulin levels Heart rate variability HRV which is the time between heartbeats is also influenced by sleep and the bodys rhythm Lower HRV levels have been linked to heart and mental health issues Little research is present on the effects of post-dinner snacks and pre-breakfast interventions on sleep quality Heart Rate Variability HRV temperature Interleukin-6 and cortisol levels It is hypothesised that eating a post-dinner snack and first pre-breakfast will affect sleep quality heart rate variability IL -6 cortisol levels and temperature in healthy males
Detailed Description:
The bodys internal clock circadian rhythms works on a 24-hour cycle and is managed by a part of the brain called the hypothalamus These rhythms control various bodily functions like temperature hunger emotions and even our sleep-wake cycle During sleep hormones like cortisol growth hormone and insulin influence processes such as glucose metabolism For instance insulin levels drop while we sleep to allow the body to use stored energy but rise again before waking Poor sleep quality even with adequate duration can lead to increased stress and elevated cortisol levels potentially affecting insulin and heart health Heart rate variability HRV is the variation in time between heartbeats and is influenced by factors like stress diet and sleep quality Lower HRV levels are associated with cardiovascular and mental health issues Disruptions in the circadian sleep cycle can also affect the gut-brain axis which involves communication between the gut and the brain via the vagus nerve This axis influences gastrointestinal function and can impact inflammatory markers like interleukin-6 IL-6 which in turn affect HRV and cardiovascular health Dietary choices play a significant role in shaping the bodys physiological processes Nuts can positively impact HRV and sleep quality due to their nutrient content A post-dinner snack consumed about three hours after dinner and a balanced pre-breakfast meal is important for maintaining stable blood sugar levels and overall health Nuts such as peanuts almonds cashews pistachios and walnuts along with raisins offer numerous health benefits These contain fibre protein healthy fats and essential nutrients that promote satiety metabolic well-being and digestive health Thus this research aims to investigate the effects of post-dinner snacks and pre-breakfast interventions on HRV sleep quality IL-6 cortisol and temperature By exploring the relationship between dietary choices and physiological processes we hope to gain insight into how to optimize health and well-being
The participation will go through 2 assessments at baseline and after intervention For comparison two-way ANOVA followed by Post hoc-Tuckey test and for correlation between HRV and other parameters will be done using Pearson Correlation
The participation will go through 2 assessments at baseline and after intervention For comparison two-way ANOVA followed by Post hoc-Tuckey test and for correlation between HRV and other parameters will be done using Pearson Correlation
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None