Ignite Creation Date:
2024-07-17 @ 11:54 AM
Last Modification Date:
2024-10-26 @ 3:32 PM
Study NCT ID:
NCT06467656
Status:
RECRUITING
Last Update Posted:
2024-06-24
First Post:
2024-05-22
Brief Title:
The UBC Long-distance Triathlon Adaptation Study
Sponsor:
University of British Columbia
Organization:
University of British Columbia
Study Overview
Official Title:
The UBC Long-distance Triathlon Adaptation Study
Status:
RECRUITING
Status Verified Date:
2024-06
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
ULTRA
Brief Summary:
The purpose of this study is to investigate the effect of 12-months of individualized endurance-training swimming cycling and running on physiological and psychological adaptations in exercise naïve individuals Due to the potential seasonal changes that naturally occur in individuals across a year even without training the investigators will also compare the exercise-trained group to a time-aligned control group
Detailed Description:
Endurance training is well-accepted to lead to numerous positive physiological and psychological adaptations However many of the previous studies examining the benefits of endurance exercise on the human body have 1 compared athletes with non-athletes using a cross-sectional design 2 have employed training studies that are relatively short eg weeks to months in duration 3 have primarily focused on male participants and not examined potential sex-differences and 4 have not specifically recruited exercise naïve participants as often participants are already engaged in ongoing recreational or competitive activities at the time of recruitment As such we have a limited understanding of the true time-course of adaptations that occur in exercise naïve individuals in response to training or how physiological and psychological adaptations change beyond 4-6 months and whether there are sex-specific differences in these adaptations
This study is primarily designed to determine the time-course of adaptation and remodeling in females and males across multiple different physiological systems ie cardiac vascular metabolic respiratory immune and microbiome and psychological measures at rest and in response to a range of provocations
Forty healthy exercise-training naïve individuals 20 females 20 males will perform 12-months of individually prescribed endurance training including supplementary strengthening exercise for conditioning and injury prevention designed to prepare participants for an ultra-endurance triathlon A time-aligned control group of 20 healthy exercise-training naïve individuals 10 females 10 males will also be recruited to determine the natural change that occurs in each system across a year Outcomes will be assessed at baseline 3 months 6 months and 12 months Additionally cardiovascular outcomes will also be assessed at 1 month and immune outcomes will be repeated at 3 months post intervention 15 months
This study is primarily designed to determine the time-course of adaptation and remodeling in females and males across multiple different physiological systems ie cardiac vascular metabolic respiratory immune and microbiome and psychological measures at rest and in response to a range of provocations
Forty healthy exercise-training naïve individuals 20 females 20 males will perform 12-months of individually prescribed endurance training including supplementary strengthening exercise for conditioning and injury prevention designed to prepare participants for an ultra-endurance triathlon A time-aligned control group of 20 healthy exercise-training naïve individuals 10 females 10 males will also be recruited to determine the natural change that occurs in each system across a year Outcomes will be assessed at baseline 3 months 6 months and 12 months Additionally cardiovascular outcomes will also be assessed at 1 month and immune outcomes will be repeated at 3 months post intervention 15 months
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None