Ignite Creation Date:
2024-07-17 @ 11:53 AM
Last Modification Date:
2024-10-26 @ 3:32 PM
Study NCT ID:
NCT06467292
Status:
RECRUITING
Last Update Posted:
2024-06-21
First Post:
2024-06-13
Brief Title:
Speech Motor Learning and Retention Master Protocol
Sponsor:
Yale University
Organization:
Yale University
Study Overview
Official Title:
Sensorimotor Basis of Speech Motor Learning and Retention
Status:
RECRUITING
Status Verified Date:
2024-10
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
The overall goal of this research is to test a new model of speech motor learning whose central hypothesis is that learning and retention are associated with plasticity not only in motor areas of the brain but in auditory and somatosensory regions as well
Detailed Description:
Aim 1 involves tests of speech motor memory retention following disruption of left hemisphere brain activity in either auditory somatosensory or motor cortex or to a control site hand area motor cortex right hemisphere Continuous theta-burst stimulation cTBS is delivered following adaptation to altered auditory feedback to assess its effects on the retention of new learning
Aim 2 assesses the temporal order in which plasticity occurs in cortical motor and sensory brain areas during speech motor learning
In Aim 3 resting-state fMRI will be interleaved with speech motor adaptation For information specific to each aim please refer to the below corresponding separate clinicaltrialsgov records unique IDs 2000037622_a for Aim 1 2000037622_b for Aim 2 and 2000037622_c for Aim 3
Aim 2 assesses the temporal order in which plasticity occurs in cortical motor and sensory brain areas during speech motor learning
In Aim 3 resting-state fMRI will be interleaved with speech motor adaptation For information specific to each aim please refer to the below corresponding separate clinicaltrialsgov records unique IDs 2000037622_a for Aim 1 2000037622_b for Aim 2 and 2000037622_c for Aim 3
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None
Secondary IDs
| Secondary ID | Type | Domain | Link |
|---|---|---|---|
| 1R01DC022097-01A1 | OTHER_GRANT | None | None |