Ignite Creation Date:
2024-07-17 @ 11:53 AM
Last Modification Date:
2024-10-26 @ 3:34 PM
Study NCT ID:
NCT06491329
Status:
NOT_YET_RECRUITING
Last Update Posted:
2024-07-09
First Post:
2024-06-22
Brief Title:
Effect of Aerobic Interval Training on Atrial Fibrillation Burden
Sponsor:
Navy General Hospital Beijing
Organization:
Navy General Hospital Beijing
Study Overview
Official Title:
Effect of Aerobic Interval Training on Atrial Fibrillation BurdenA Multicenter Randomized Controlled Study
Status:
NOT_YET_RECRUITING
Status Verified Date:
2024-06
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
Atrial fibrillation is the most common arrhythmia with an increasing incidence and prevalence significantly increasing the risk of death stroke heart failure cognitive impairment and dementia severely impacting the quality of life for patients and burdening society and healthcare systems In recent years exercise-based cardiac rehabilitation has gradually become a new approach for the treatment of patients with heart disease The main research topics include 1 Changes in atrial fibrillation burden in non-permanent atrial fibrillation patients after 12 weeks of HIIThigh-intensity interval training or MIIT moderate-intensity interval training 2 Changes in cardiorespiratory fitness quality of life scores mental health assessment scores atrial strain and left ventricular diastolic function in non-permanent atrial fibrillation patients after 12 weeks of aerobic interval training along with follow-up on the occurrence of exercise-related adverse events and adverse cardiovascular events during the study period
Detailed Description:
This study is a multicenter prospective randomized clinical trial It aims to enroll a total of 156 patients with non-permanent atrial fibrillation Participants will be randomly assigned to the HIIT group MIIT group and control group The HIIT and MIIT groups will receive 12 weeks of high-intensity interval aerobic exercise training and moderate-intensity interval aerobic exercise training respectively while the control group will maintain their previous exercise habitsThe study will compare the atrial fibrillation burden cardiorespiratory fitness quality of life scores mental health scale scores blood lipids blood glucose levels atrial strain and ventricular diastolic function changes among patients in the different exercise intervention groups and the control group after 12 weeks Additionally the occurrence rates of exercise-related adverse events and cardiovascular adverse events during the follow-up period will be assessed to evaluate the effectiveness and safety of cardiac rehabilitation in the treatment of atrial fibrillation patients
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None