Ignite Creation Date:
2024-07-17 @ 11:52 AM
Last Modification Date:
2024-10-26 @ 3:32 PM
Study NCT ID:
NCT06471491
Status:
RECRUITING
Last Update Posted:
2024-06-24
First Post:
2024-05-31
Brief Title:
Driving Pressure-guided Positive End-expiratory Pressure to Prevent Postoperative Atelectasis in Obese Children a Prospective Randomized Controlled Clinical Trial
Sponsor:
Henan Provincial Peoples Hospital
Organization:
Henan Provincial Peoples Hospital
Study Overview
Official Title:
Driving Pressure-guided Positive End-expiratory Pressure to Prevent Postoperative Atelectasis in Obese Children a Prospective Randomized Controlled Clinical Trial
Status:
RECRUITING
Status Verified Date:
2024-06
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
At present the use of lung protective ventilation strategies in children is mainly based on adult and intensive care unit data Although obese children may benefit more from lung protective ventilation there are few studies on the use of lung protective ventilation strategies in obese children during surgery Therefore the investigators hypothesized that intraoperative use of LPV strategies in obese pediatric surgery patients can reduce atelectasis and improve the incidence of postoperative pulmonary complications
Detailed Description:
In the lung protective ventilation group PEEP was titrated individually in a sequential manner after mechanical ventilation According to previous studies PEEP was 5 cmH2O inspiratory pressure was 20 cmH2O and respiratory rate was set according to patient age PEEP and inspiratory pressure were increased by 5 cmH2O every 30 seconds until PEEP was 15 cmH2O and inspiratory pressure 30 cmH2O This was followed by a decreasing amplitude of 2 cmH2O to 3 cmH2O starting from 15 cmH2O and each PEEP level was maintained for 4 to 5 respiratory cyclesThe PEEP was at the lowest driving pressure was applied throughout the procedure The PEEP level resulting in the lowest driving pressure was applied during surgery In the traditional mechanical ventilation group a fixed PEEP of 5 cm H2O was applied The investigators compared the incidence of postoperative atelectasis between the two groups using lung ultrasound
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None