Ignite Creation Date:
2024-07-17 @ 11:52 AM
Last Modification Date:
2024-10-26 @ 3:32 PM
Study NCT ID:
NCT06465082
Status:
RECRUITING
Last Update Posted:
2024-06-21
First Post:
2024-06-13
Brief Title:
Diaphragmatic Thickening Fraction as a Predictor of Successful Weaning
Sponsor:
Mansoura University Hospital
Organization:
Mansoura University Hospital
Study Overview
Official Title:
Role of Diaphragmatic Thickening Fraction as a Predictor of Successful Weaning From Mechanical Ventilation
Status:
RECRUITING
Status Verified Date:
2024-10
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
The aim of this study is to assess the validity of the diaphragmatic thickening Fraction measured by ultrasound as a predictor for successful weaning from mechanical ventilation
Detailed Description:
Timing is critical for proper weaning for patients undergoing mechanical ventilation if this is performed prematurely complications can include increased cardiovascular and respiratory stress CO2 retention and hypoxemia However unnecessary delay in weaning can also cause a number of side-effectsWeaning outcomes have been assessed by several indices Variables such as minute ventilation Pao2Fio2 rapid shallow breathing index and static compliance have all been used with variable predictive values Previous studies have proved that diaphragmatic dysfunction is one of the main etiologies of difficult weaning because the diaphragm progressively weakens with mechanical ventilationMethods used to assess diaphragm function such as fluoroscopy phrenic nerve stimulation measurement of trans-diaphragmatic pressure and dynamic magnetic resonance imaging of the diaphragm all have limitations These include ionizing radiation exposure low availability invasiveness and necessity for patient transportation Conversely the use of ultrasound is safe non-invasive avoids radiation side-effects and is available at the bedsideThe aim of this study is to assess the validity of the diaphragmatic thickening Fraction measured by ultrasound as a predictor for successful weaning from mechanical ventilation
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None