Ignite Creation Date:
2024-07-17 @ 11:51 AM
Last Modification Date:
2024-10-26 @ 3:33 PM
Study NCT ID:
NCT06476587
Status:
ACTIVE_NOT_RECRUITING
Last Update Posted:
2024-06-26
First Post:
2024-05-22
Brief Title:
Idiopathic Bilateral Vestibulopathy Peripheral Vestibular Disorders and Their Repercussions
Sponsor:
University Hospital Caen
Organization:
University Hospital Caen
Study Overview
Official Title:
Vestibulopathie bilatérale Idiopathique caractérisation Des Atteintes Vestibulaires périphériques et de Leurs Retentissements Posturaux végétatifs émotionnels et Cognitifs
Status:
ACTIVE_NOT_RECRUITING
Status Verified Date:
2024-04
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
VBI
Brief Summary:
The goal of this exploratory study is to gain a better understanding of the symptomatology of idiopathic bilateral vestibulopathy IBV by characterising as precisely as possible the type and intensity of each patients peripheral vestibular deficit and to investigate the link between this symptomatology and some functions influenced by the vestibular system ie cognitive emotional vegetative functions
Detailed Description:
Bilateral vestibulopathy BV is defined as total or partial impairment of vestibular function on both sides leading to chronic postural and visual instability Idiopathic bilateral vestibulopathy IBV is a rare condition characterised by acquired BV of unknown aetiology Although described more than thirty years ago IBV remains a condition with imperfectly understood contours mechanisms and consequences
The peripheral vestibular system located in the inner ear is the main balance organ Sensory information from the vestibular system is distributed to different brain structures which perform a wide range of functions such as maintaining stability of gaze and posture controlling certain functions such as sleep spatial memory and emotional processes and perceiving movement spatial orientation and self-image
The most common symptoms of IBV are persistent postural instability and when moving the head and body a reduction in visual acuity that can go as far as a sensation of instability of the visual environment Patients also often report problems with orientation and spatial memory poor body shape sleep disorders attentional problems and anxiety or depression Because little is known about this disease diagnosis often comes late after several years of various explorations and consultations with doctors and specialists
Based on the observation that patients suffering from IBV have heterogeneous peripheral impairments both qualitatively type of sensory organ affected and quantitatively the impairment is more or less complete and that the sometimes complex symptomatology is difficult to relate to the type of peripheral deficit the aim of this project is to gain a better understanding of the symptomatology of IBV by evaluating certain functions that have recently been shown to be influenced by the vestibular system and to relate this to the type and intensity of the peripheral deficit
Hence the main aim of this project is to study the link between symptomatology - both classic posturo-oculomotor and cognitive emotional and vegetative - and the type and intensity of vestibular disorder
The peripheral vestibular system located in the inner ear is the main balance organ Sensory information from the vestibular system is distributed to different brain structures which perform a wide range of functions such as maintaining stability of gaze and posture controlling certain functions such as sleep spatial memory and emotional processes and perceiving movement spatial orientation and self-image
The most common symptoms of IBV are persistent postural instability and when moving the head and body a reduction in visual acuity that can go as far as a sensation of instability of the visual environment Patients also often report problems with orientation and spatial memory poor body shape sleep disorders attentional problems and anxiety or depression Because little is known about this disease diagnosis often comes late after several years of various explorations and consultations with doctors and specialists
Based on the observation that patients suffering from IBV have heterogeneous peripheral impairments both qualitatively type of sensory organ affected and quantitatively the impairment is more or less complete and that the sometimes complex symptomatology is difficult to relate to the type of peripheral deficit the aim of this project is to gain a better understanding of the symptomatology of IBV by evaluating certain functions that have recently been shown to be influenced by the vestibular system and to relate this to the type and intensity of the peripheral deficit
Hence the main aim of this project is to study the link between symptomatology - both classic posturo-oculomotor and cognitive emotional and vegetative - and the type and intensity of vestibular disorder
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None