Ignite Creation Date:
2024-07-17 @ 11:51 AM
Last Modification Date:
2024-10-26 @ 3:34 PM
Study NCT ID:
NCT06494306
Status:
NOT_YET_RECRUITING
Last Update Posted:
2024-07-10
First Post:
2024-07-02
Brief Title:
Characterization of Olfactory Perception in Post-Traumatic Stress Disorder
Sponsor:
Hospices Civils de Lyon
Organization:
Hospices Civils de Lyon
Study Overview
Official Title:
Characterization of Olfactory Perception in Post-Traumatic Stress Disorder
Status:
NOT_YET_RECRUITING
Status Verified Date:
2024-06
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
TRAUMODO
Brief Summary:
The core symptoms of post-traumatic stress disorder PTSD include flash backs intrusive pictures and thoughts related to the traumatic event hyperalertness avoidance of traumatic relevant environmental triggers and emotional dysregulation Some studies suggest that PTSD is also associated with impaired olfactory perception which seems quite intuitive regarding the close anatomical-functional connections between olfactory and emotional circuits Furthermore some studies reported that olfactory stimuli can trigger flashbacks in subjects with PTSD However up to know available data is scarce and heterogeneous concerning that topic The goal of the study is to determine the olfactory phenotype of subjects with PTSD More precisely this project aims at filling the above mentioned gap by systematically assessing the olfactory perception of subjects with PTSD along five dimensions olfactory identity hedonic value familiarity desirability and edibility As a secondary goal the relative weight of olfaction compared to the other senses in the relived memories of subjects with PTSD will be assessed
The investigators here hypothesize a global impairment in olfactory processing intensity hedonicity familiarity and edibility judgments in PTSD subjects compared with healthy subjects
The investigators here hypothesize a global impairment in olfactory processing intensity hedonicity familiarity and edibility judgments in PTSD subjects compared with healthy subjects
Detailed Description:
None
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None