Ignite Creation Date:
2024-07-17 @ 11:51 AM
Last Modification Date:
2024-10-26 @ 3:33 PM
Study NCT ID:
NCT06478940
Status:
NOT_YET_RECRUITING
Last Update Posted:
2024-06-27
First Post:
2024-06-23
Brief Title:
3Mixtatin and MTA Vital Pulpotomy in Primary Molars
Sponsor:
Cairo University
Organization:
Cairo University
Study Overview
Official Title:
Clinical and Radiographic Evaluation of 3Mixtatin Versus MTA Used as Pulpotomy Agents in Vital Primary Molars A Randomized Clinical Trial
Status:
NOT_YET_RECRUITING
Status Verified Date:
2024-06
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
The aim of the study is to evaluate clinical and radiographic success of using 3Mixtain versus mineral trioxide aggregate in pulpotomy of deeply carious Primary molars
Detailed Description:
Due to the complexity of the root canal microbiome it is doubtful that they can be treated properly with a single antibiotic Accordingly a combination of multiple antibiotics seemed to be essential to diminish different types of pathogenic bacteria Recently a combination of three antibiotics Metronidazole cefixime and Ciprofloxacin along with Statins new bio-inductive materials in regenerative dentistry has shown promising results in primary teeth pulp therapy
Statin components have an anti-inflammatory impact on pulp tissue by lowering the amount of interleukin-6 and interleukin-8 They also decrease osteoclastic processes and strengthen osteoblastic processes Thus they promote bone regeneration and dentin formation by enhancing odontoblastic activity Several studies have shown a clinical and radiographic success rate of 3Mixtatin with inconsistent results Some randomized controlled Trials RCTs showed that MTA had a comparable result with 3Mixtatin while others reported that 3Mixtatin might be an alternative for MTA due to its higher overall success rate 3Mixtatin is considered as a novel material with successful outcomes Owing to limited availability of data in researches and in order to reach a conclusive results our study aims to evaluate clinical and radiographic success of using 3Mixtain versus mineral trioxide aggregate in pulpotomy of deeply carious Primary molars
Statin components have an anti-inflammatory impact on pulp tissue by lowering the amount of interleukin-6 and interleukin-8 They also decrease osteoclastic processes and strengthen osteoblastic processes Thus they promote bone regeneration and dentin formation by enhancing odontoblastic activity Several studies have shown a clinical and radiographic success rate of 3Mixtatin with inconsistent results Some randomized controlled Trials RCTs showed that MTA had a comparable result with 3Mixtatin while others reported that 3Mixtatin might be an alternative for MTA due to its higher overall success rate 3Mixtatin is considered as a novel material with successful outcomes Owing to limited availability of data in researches and in order to reach a conclusive results our study aims to evaluate clinical and radiographic success of using 3Mixtain versus mineral trioxide aggregate in pulpotomy of deeply carious Primary molars
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None