Ignite Creation Date:
2024-07-17 @ 11:45 AM
Last Modification Date:
2024-10-26 @ 3:32 PM
Study NCT ID:
NCT06463106
Status:
COMPLETED
Last Update Posted:
2024-06-17
First Post:
2024-06-12
Brief Title:
Endothelial Dysfunction in Post-infection Fatigue Syndromes
Sponsor:
FH Joanneum Gesellschaft mbH
Organization:
FH Joanneum Gesellschaft mbH
Study Overview
Official Title:
Endothelial Dysfunction in Post-infection Fatigue Syndromes
Status:
COMPLETED
Status Verified Date:
2024-06
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
Post-infection chronic fatigue syndromes such as myalgic encephalomyelitischronic fatigue syndrome MECFS and post-COVID-19 condition Long Covid are conditions primarily characterized by debilitating fatigue This fatigue can range from mild where patients are still able to participate in some social activities eg school work to moderate and severe where sufferers are predominantly homebound and bedridden As a result MECFS and Long Covid not only negatively impact the quality of life of affected individuals and their caregivers but also represent a substantial and often silent burden on healthcare systems worldwide including Austria This is primarily because most cases remain undiagnosed due to the lack of standardized clinical assessments and diagnostic markers Endothelial dysfunction which is well known to affect blood flow oxygen and nutrient delivery and waste removal in the body has been described as one of the key factors behind the symptoms experienced by MECFS and Long Covid patients However the mechanisms that might explain the development of endothelial dysfunction remain largely unexplored Therefore this project aims to evaluate key biological aspects related to the function of endothelial cells - a layer of cells lining blood vessels - using plasma samples from an Austrian cohort of MECFS and Long Covid patients We expect that the findings from our study will provide new insights to better understand endothelial dysfunction in post-infection chronic fatigue syndromes leading to improved patient stratification and tailored treatment alternatives
Detailed Description:
None
Study Oversight
Has Oversight DMC:
Is a FDA Regulated Drug?:
Is a FDA Regulated Device?:
Is an Unapproved Device?:
Is a PPSD?:
Is a US Export?:
Is an FDA AA801 Violation?: