Ignite Creation Date:
2024-07-17 @ 11:39 AM
Last Modification Date:
2024-10-26 @ 3:33 PM
Study NCT ID:
NCT06472609
Status:
RECRUITING
Last Update Posted:
2024-06-25
First Post:
2023-05-26
Brief Title:
Prospective Quality Improvement Project for High-Risk Diabetes Patients
Sponsor:
Taipei Medical University WanFang Hospital
Organization:
Taipei Medical University WanFang Hospital
Study Overview
Official Title:
Prospective Quality Improvement Project for High-Risk Diabetes Patients
Status:
RECRUITING
Status Verified Date:
2024-04
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
Diabetes is the most important comorbidity of tuberculosis patients in Taiwan and 14 of tuberculosis patients also It is a diabetic patient and the treatment of latent tuberculosis infection is currently an important policy of the Taiwan Disease Control Agency One because babies are prone to encounter difficulties in the early stages because of the spread of Australian patients in the community The Department of Disease Control encourages patients with diabetes to receive screening and treatment for latent tuberculosis infection
Detailed Description:
Diabetes mellitus is the most prevalent comorbiditiy for patients with active tuberculosis in Taiwan More than one fourth of the patients with incident tuberculosis has diabetes mellitus The latent tuberculosis infection treatment is recommended by the Centers of Disease Control CDC of Taiwan to halt the transmission of tuberculosis in the community Considering a relatively long delay in diagnosis of tuberculosis in clinical practice eliminate the dormant tuberculosis germs a the stage of latent infection is the most cost-effective strategy to avoid tuberculosis transmission The population with diabetes mellitus and inadequate blood sugar control are at increased risk of latent tuberculosis infection and activation and are encouraged to undergo latent tuberculosis screening and treatment However the anti-tuberculosis agents could have significant drug-drug interaction with the drugs used for diabetes mellitus control The extent of its impact on blood sugar is still unclear We aim to investigate the fluctuation of blood sugar during latent tuberculosis treatment with continuous subcutaneous sugar monitoring device to evaluate the possible associated risk of hyperglycemia or hypoglycemia to enhance treatment safety Inadequate blood sugar control is the root for immune dysfunction and render the patients vulnerable to infectious diseases Hence improvement in the blood sugar control not only leads to a better immune function to avoid tuberculosis infection but also reduce the risk of progression for cardiovascular and renal disorder The present study proposed a protocol of 12-week aggressive blood sugar control and education program using phone call to improve the blood sugar control and life quality Furthermore to evaluate the efficacy of anti-tuberculosis treatment for latent tuberculosis we propose to evaluate the mycobacteria-specific antigen immune response by using the interferon-gamma releasing assay before and after anti-tuberculosis treatment
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None