Ignite Creation Date:
2024-07-17 @ 11:37 AM
Last Modification Date:
2024-10-26 @ 3:34 PM
Study NCT ID:
NCT06495658
Status:
RECRUITING
Last Update Posted:
2024-07-11
First Post:
2024-04-03
Brief Title:
Impact of Prebiotics in Ulcerative Colitis
Sponsor:
University of California Los Angeles
Organization:
University of California Los Angeles
Study Overview
Official Title:
The Clinical and Microbial Impact of Prebiotics in Ulcerative Colitis
Status:
RECRUITING
Status Verified Date:
2024-07
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
The cause of inflammatory bowel disease IBD is currently unknown although partly attributed to interactions among genetic risk polymorphisms environmental factors gut microbiome and host immunity Diet particularly those with plant-based products have been shown in prior research to improve gut microbial composition which has been linked to different IBD-related outcomes This study is interested in evaluating the impact of prebiotics on gut microbiome composition and gut health in patients with IBD
Dietary composition will be assessed at baseline and over the course of 16 weeks Participants will be randomized to either consume an 8-week course of prebiotic supplementation beginning at week 0 or week 8 Stool samples will be collected at weeks 0 and 8 The stool will be analyzed for cross-sectional and longitudinal fecal microbial changes associated with different prebiotic and diet consumption patterns in the context of heterogeneous disease characteristics
Dietary composition will be assessed at baseline and over the course of 16 weeks Participants will be randomized to either consume an 8-week course of prebiotic supplementation beginning at week 0 or week 8 Stool samples will be collected at weeks 0 and 8 The stool will be analyzed for cross-sectional and longitudinal fecal microbial changes associated with different prebiotic and diet consumption patterns in the context of heterogeneous disease characteristics
Detailed Description:
None
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None