Ignite Creation Date:
2024-07-17 @ 11:34 AM
Last Modification Date:
2024-10-26 @ 3:32 PM
Study NCT ID:
NCT06462274
Status:
RECRUITING
Last Update Posted:
2024-06-17
First Post:
2016-01-31
Brief Title:
Biomarkers and Imaging Markers for ICH
Sponsor:
Southwest Hospital China
Organization:
Southwest Hospital China
Study Overview
Official Title:
Biomarkers and Imaging Markers Screening for Intracerebral Hemorrhage Patients
Status:
RECRUITING
Status Verified Date:
2024-06
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
Intracerebral hemorrhage ICH is a subtype of stroke associated with high mortality and disability Basic and clinical research has contributed to our understanding of the complex pathophysiology in ICH However questions regarding acute diagnosis therapeutic decisions and prognostication of ICH remain unanswered Molecular biomarkers and imaging markers have revolutionalized diagnosis and treatment of many diseases such as troponin use in myocardial infarction and magnetic resonance imaging MRI scan in ischemic stroke Therefore the investigators aim to discovery the potential biomarkers by screening samples of blood cerebral spinal fluid urine saliva and even tissues if available from ICH patients and imaging markers via serial multimodality imaging scans such as computed tomographyCT magnetic resonance imaging MRI magnetic resonance spectroscopy MRS positron emission tomography PET etc These molecular and imaging markers would assist in contributing additional information to current tools for onset warning diagnosis therapy monitoring risk stratification intervention and prognosis for ICH patients
Detailed Description:
Intracerebral hemorrhage ICH is one of the most serious subtypes of stroke affecting approximately 2-3 million people worldwide each year About one third of people with ICH die early after onset and the majority of survivors are left with major long-term disability Today little is known about the characteristic changes in molecules from body samples and pictures from multimodality imaging scans In this study the investigators aim to reveal the potential biomarkers by screening samples of blood cerebral spinal fluid urine saliva and even tissues if available from ICH patients and imaging markers via serial multimodality imaging scans such as computed tomographyCT magnetic resonance imaging MRI magnetic resonance spectroscopy MRS positron emission tomography PET etc which will bring insights into pathophysiological mechanisms and addition of new tools for onset warning diagnosis therapy monitoring risk stratification intervention and prognosis for ICH patients
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None