Ignite Creation Date:
2024-07-17 @ 11:33 AM
Last Modification Date:
2024-10-26 @ 3:34 PM
Study NCT ID:
NCT06496022
Status:
ACTIVE_NOT_RECRUITING
Last Update Posted:
2024-07-15
First Post:
2024-07-03
Brief Title:
Comparative Analysis of Risk Factors and Prediction of Frailty Syndrome
Sponsor:
Asfendiyarov Kazakh National Medical University
Organization:
Asfendiyarov Kazakh National Medical University
Study Overview
Official Title:
Comparative Analysis of Risk Factors and Prediction of Frailty Syndrome
Status:
ACTIVE_NOT_RECRUITING
Status Verified Date:
2024-07
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
FRAILTY-KZ
Brief Summary:
Assessing frailty syndrome in elderly patients in Almaty To study the features of the clinical course in the group of patients with a pre-frailty and in the group with frailty syndrome
Detailed Description:
2 cohorts of patients a group of patients with pre-frailty 300 patients and a group of patients with frailty syndrome 300 patients
Comparative analysis of the indicators of two groups demographic laboratory indicators scale results
To study the features of the clinical course of frailty To determine the risk factors for the development of frailty To identify criteria for an unfavorable outcome of frailty
The study will involve patients over the age of 60 The recruitment of patients will be carried out in polyclinics and nursing homes in Kazakhstan
The collection of primary information and a comprehensive examination of patients will be based on the following research methods recommended by WHO
1 Measurements of anthropometric data for calculating body mass index
2 orthostatic test active with measurement of blood pressure heart rate in horizontal and vertical positions Blood pressure is measured by the auscultative method Korotkov method
3 Survey-based tests
the Bartel scale for determining the degree of independence in daily life the patients household activity assessing the quality of life and the necessary care
The Food Frequency Questionnaire on food preferences over the last 4-week period and the MNA questionnaire on the detection of malnutrition
FRAIL scale for determining senile asthenia tired most of the time in the last 4 weeks presence of more than 5 diseases difficulty or inability when climbing stairs and walking around the block weight loss of more than 5 of the previous weight in the last 6 months
SARC-F scale for detecting muscle dysfunction difficulty lifting things over 45 kg walking around the room difficulty climbing from a chair and up 10 steps whether the respondent has fallen in the last year
FRAX scale Kazakhstan platform assessment of fracture and osteoporosis risk on the website httpsfraxshefacukFRAXtoolaspxcountry72
Mini-Cog scale for determining cognitive impairment cognitive impairment - when scoring less than 3 points based on remembering three words and evaluating the task of drawing a clock
4 carpal dynamometry sarcopenia is exhibited at values below 26 units for men and below 16 units for women
5 Laboratory parameters uric acid serum creatinine calculated using the CKD-EPI formula creatinine clearance according to the Cockcroft-Gault formula blood iron levels blood ferritin vitamin B12 in the blood folate in the blood total protein and albumin in the blood 25-OH vitamin D in the blood
Comparative analysis of the indicators of two groups demographic laboratory indicators scale results
To study the features of the clinical course of frailty To determine the risk factors for the development of frailty To identify criteria for an unfavorable outcome of frailty
The study will involve patients over the age of 60 The recruitment of patients will be carried out in polyclinics and nursing homes in Kazakhstan
The collection of primary information and a comprehensive examination of patients will be based on the following research methods recommended by WHO
1 Measurements of anthropometric data for calculating body mass index
2 orthostatic test active with measurement of blood pressure heart rate in horizontal and vertical positions Blood pressure is measured by the auscultative method Korotkov method
3 Survey-based tests
the Bartel scale for determining the degree of independence in daily life the patients household activity assessing the quality of life and the necessary care
The Food Frequency Questionnaire on food preferences over the last 4-week period and the MNA questionnaire on the detection of malnutrition
FRAIL scale for determining senile asthenia tired most of the time in the last 4 weeks presence of more than 5 diseases difficulty or inability when climbing stairs and walking around the block weight loss of more than 5 of the previous weight in the last 6 months
SARC-F scale for detecting muscle dysfunction difficulty lifting things over 45 kg walking around the room difficulty climbing from a chair and up 10 steps whether the respondent has fallen in the last year
FRAX scale Kazakhstan platform assessment of fracture and osteoporosis risk on the website httpsfraxshefacukFRAXtoolaspxcountry72
Mini-Cog scale for determining cognitive impairment cognitive impairment - when scoring less than 3 points based on remembering three words and evaluating the task of drawing a clock
4 carpal dynamometry sarcopenia is exhibited at values below 26 units for men and below 16 units for women
5 Laboratory parameters uric acid serum creatinine calculated using the CKD-EPI formula creatinine clearance according to the Cockcroft-Gault formula blood iron levels blood ferritin vitamin B12 in the blood folate in the blood total protein and albumin in the blood 25-OH vitamin D in the blood
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None