Ignite Creation Date:
2024-07-17 @ 11:31 AM
Last Modification Date:
2024-10-26 @ 3:33 PM
Study NCT ID:
NCT06477627
Status:
ACTIVE_NOT_RECRUITING
Last Update Posted:
2024-06-27
First Post:
2024-06-21
Brief Title:
The Coastal Exposome a Study of Sea Air Inhalation and Possible Links to Health
Sponsor:
University Ghent
Organization:
University Ghent
Study Overview
Official Title:
The Coastal Exposome a Study of Sea Air Inhalation and Possible Links to Health
Status:
ACTIVE_NOT_RECRUITING
Status Verified Date:
2024-08
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
The research aims to understand oceans as crucial contributors to human health in coastal environments Oceans produce marine spray aerosols that contain a mixture of microbiota and natural biological molecules biogenics
Detailed Description:
The primary outcome envisioned consists of 2 goals
1 In this study the first objective is to determine whether the microbiota and biogenic molecules found in sea air are also found in the nasal swabs of the participants In this way the investigators will gain an understanding of which sea air components are inhaled by humans and how this changes over time
2 Second the investigators want to get an idea of whether these inhaled sea air components have an effect on certain pathways in the human body In the in vitro study with cell lines effects were already seen of sea air exposure on certain pathways in the body Now the second goal of this study is to see if changes in immunity biomarkers IL-6 TNF-alpha IL-10 are seen in vivo in humans The Investigators will do this by taking VAMS blood samples from the participants
1 In this study the first objective is to determine whether the microbiota and biogenic molecules found in sea air are also found in the nasal swabs of the participants In this way the investigators will gain an understanding of which sea air components are inhaled by humans and how this changes over time
2 Second the investigators want to get an idea of whether these inhaled sea air components have an effect on certain pathways in the human body In the in vitro study with cell lines effects were already seen of sea air exposure on certain pathways in the body Now the second goal of this study is to see if changes in immunity biomarkers IL-6 TNF-alpha IL-10 are seen in vivo in humans The Investigators will do this by taking VAMS blood samples from the participants
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None