Ignite Creation Date:
2024-07-17 @ 11:31 AM
Last Modification Date:
2024-10-26 @ 3:34 PM
Study NCT ID:
NCT06497023
Status:
COMPLETED
Last Update Posted:
2024-07-11
First Post:
2024-06-23
Brief Title:
Radiomics Model Based on DCE-MRI and Ultrasound Images for Breast Lesion Classification
Sponsor:
Ma Zhe
Organization:
Qianfoshan Hospital
Study Overview
Official Title:
Multi-modality Radiomics Diagnostic Model Based on DCE-MRI and Ultrasound Images for Benign and Malignant Breast Lesion Classification
Status:
COMPLETED
Status Verified Date:
2024-07
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
To develop and compare multi-modality radiomics models based on DCE-MRI B-mode ultrasound BMUS and strain elastography SE images for classifying benign and malignant breast lesions
Detailed Description:
In this retrospective study555 breast lesions from 555 patients who underwent DCE-MRI BMUS and SE examinations were randomly divided into training n 388 and testing n 167 datasets Radiomics features were extracted from manually contoured images The inter-class correlation coefficient ICC Mann-Whitney U test and the least absolute shrinkage and selection operator LASSO regression was applied for feature selection and radiomics signature buildingNine radiomics models including four single-modality radiomics models DCE-3D DCE-2D BMUS and SE four multi-modality radiomics models BMUS SE DCE-3D BMUS DCE-3D SE and DCE-3DSEBMUS and the combination diagnostic modelclinical features and DCE-3DSEBMUS features were developed and evaluated by their discrimination calibration and clinical usefulness
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None