Ignite Creation Date:
2024-07-17 @ 11:27 AM
Last Modification Date:
2024-10-26 @ 3:32 PM
Study NCT ID:
NCT06470711
Status:
RECRUITING
Last Update Posted:
2024-06-24
First Post:
2024-06-18
Brief Title:
Mapping of Electrical Properties in the Brain
Sponsor:
Mayo Clinic
Organization:
Mayo Clinic
Study Overview
Official Title:
Mapping of Electrical Properties in the Brain
Status:
RECRUITING
Status Verified Date:
2024-09
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
This study evaluates imaging methods for monitoring neural and electrical activity in the brain for improving clinical diagnosis
Detailed Description:
PRIMARY OBJECTIVES
I Optimize pulse sequence acquisitions for diffusion imaging on clinical MRI vendor systems
II Develop image-based MRI models including diffusion-based MRI that accurately depict the multi-regional electrical properties in the brain eg resistivity current to inform of neural integrity and function including white matter tract integrity in diseased and non-diseased states
III Comparecorrelate image-based MRI models eg diffusion with existing structural physiologic and functional MRI methods eg tensor imaging fMRI DSC-MRI etc
IV Further train image-based modelsmeasurements with loco-regional benchmarks including but not exclusive to electrophysiologic monitoring functional and structural tissue assays from available biopsies and correlative clinical features eg histology outcomes treatment etc
OUTLINE This is an observational study
Participants complete a survey and undergo MRI on study
I Optimize pulse sequence acquisitions for diffusion imaging on clinical MRI vendor systems
II Develop image-based MRI models including diffusion-based MRI that accurately depict the multi-regional electrical properties in the brain eg resistivity current to inform of neural integrity and function including white matter tract integrity in diseased and non-diseased states
III Comparecorrelate image-based MRI models eg diffusion with existing structural physiologic and functional MRI methods eg tensor imaging fMRI DSC-MRI etc
IV Further train image-based modelsmeasurements with loco-regional benchmarks including but not exclusive to electrophysiologic monitoring functional and structural tissue assays from available biopsies and correlative clinical features eg histology outcomes treatment etc
OUTLINE This is an observational study
Participants complete a survey and undergo MRI on study
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None
Secondary IDs
| Secondary ID | Type | Domain | Link |
|---|---|---|---|
| NCI-2024-04689 | REGISTRY | None | None |
| 24-003556 | OTHER | None | None |