Ignite Creation Date:
2024-07-17 @ 11:26 AM
Last Modification Date:
2024-10-26 @ 3:32 PM
Study NCT ID:
NCT06463756
Status:
RECRUITING
Last Update Posted:
2024-06-18
First Post:
2024-06-12
Brief Title:
AI Models to Predict Thyroid Cartilage Invasion in Laryngeal Carcinoma
Sponsor:
First Affiliated Hospital of Chongqing Medical University
Organization:
First Affiliated Hospital of Chongqing Medical University
Study Overview
Official Title:
CT-based Radiomics Two-dimensional and Three-dimensional Deep Learning Models to Predict Thyroid Cartilage Invasion in Laryngeal Carcinoma a Multicenter Study
Status:
RECRUITING
Status Verified Date:
2024-08
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
This retrospective study was to develop and verify CT-based AI model to preoperatively predict the thyroid cartilage invasion of laryngeal cancer patients so as to provide more accurate diagnosis and treatment basis for clinicians In addition the researchers investigated the prediction of survival outcomes of patients by the above optimal models
Detailed Description:
Laryngeal squamous cell carcinoma LSCC as one of the most common head and neck tumors is the eighth leading cause of cancer-associated death worldwide The treatment decisions has a profound impact on both tumor control and functional prognosis of LSCC patients And these decisions are primarily based on tumor staging with the invasion of the thyroid cartilage serving as a crucial determinant Consequently the presence of thyroid cartilage invasion indicates an advanced stage T3 or T4 diagnosis for the LSCC patients For patients without thyroid cartilage invasion partial laryngectomy may be considered to preserve laryngeal function However for patients with advanced laryngeal carcinoma and thyroid cartilage invasion extending beyond the larynx total laryngectomy is often necessary to completely remove the tumor and extend survival time Therefore accurate assessment of thyroid cartilage invasion is vital for treatment decision-making and prognosis evaluation for LSCC patients
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None