Ignite Creation Date:
2024-07-17 @ 11:26 AM
Last Modification Date:
2024-10-26 @ 3:33 PM
Study NCT ID:
NCT06482411
Status:
RECRUITING
Last Update Posted:
2024-07-03
First Post:
2024-06-17
Brief Title:
Risk Factors Affect Weight Loss Outcomes After Treatment WRRFA
Sponsor:
E-DA Hospital
Organization:
E-DA Hospital
Study Overview
Official Title:
Exploration of Effect Weight Loss Outcome Related to Factors After Treatment of Weight Loss WRRFA
Status:
RECRUITING
Status Verified Date:
2024-07
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
The treatment for weight loss was more diverse due to the higher prevalence of obesity In addition to weight loss medications many patients seek bariatric surgery to treat obesity Although bariatric surgery was the most effective way the patients still get weight gain due to failure to control their lives The failure weight loss is caused by complex risk factors such as dietary habits quality of life physical inactivity comorbidities remission rate and more related to the failure weight loss factors To explore weight gain factors the study uses many questionnaires including demographic parameter and exercise frequency survey the WHOQOL-BREF assessment The Bariatric Quality of Life Questionnaire BQL the Three-Factor Eating Questionnaire TFEQ-R18 the Yale Food Addiction Scale version 20 YFAS 20 and Depression Anxiety Stress Scales-21 DASS-21 The investigators assess different factors like quality of life food addiction preferences psychological status and regular examination parameters to identify reasons for unsuccessful weight loss The study aims to establish the model for the prediction of risk factors after treatment of weight loss so that the tools will help to manage the best weight control for the future
Detailed Description:
Obesity is a disease worldwide Hence many patients seek many different treatments for obesity The methods for obesity include medical and surgical treatment The medicine treatment indication for diabetes previously increased indication to weight loss for obese patients now Recently the four approved weight loss medicines by the Taiwan Food and Drug Administration TFDA include Orlistat Liraglutide Contrave and Semaglutide In addition to medications for weight loss indications for more than 30 body mass index BMI and more than 27 BMI with uncontrol obesity-related comorbidities
Another weight loss treatment was bariatric surgery The surgical treatment focuses on morbidity obese patients Decrease food intake and absorb calories by changing the structure of the stomach and intestine to weight loss and improve comorbidities Moreover three functions for bariatric surgery by different mechanisms to weight loss outcome include 1 restriction 2 malabsorption 3 mixed function and which indication for more than 375 BMI and more than 325 BMI with two or more uncontrol obesity-related comorbidities
Since obesity is not a condition that can be cured by surgical removal of lesions forever patients often experience weight loss failure after receiving both medical and surgical treatments Particularly the probability of weight loss failure after medical treatment is higher than that after surgical treatment Complexed risk factors caused failure weight loss from behavioral dietary quality of life remission rate of comorbidities genetic inheritance physical Inactivity and psychological status Moreover failure weight loss has two definitions 1 weight regain WR and 2 insufficient weight loss IWL The investigators searched many studies to organize failure weight loss definitions referenced by Surgery for Obesity and Related Disease SORD in the American Society for Metabolic and Bariatric Surgery ASMBS IWL is defined as less than 50 percent excess weight loss EWL or less than 35 BMI after 18 months WR is defined as 1 more than the nadir weight of 10 kg 2 more than the nadir weight of 25 EWL 3 more than the nadir weight of 5 BMI 4 successfully reduced to a BMI below 35 but after 1-year post-treatment it exceeded BMI 35 5 at any point within 1-year post-treatment the weight is higher than the lowest weight achieved 6 the weight regained is more than 15 of the lowest weight achieved In contrast to weight gain after medicine which is defined by population proportion 5 10 15 20 statistical analysis
The study was an observational cohort study The investigators will use the six types of questionnaires 1 Demographic parameters and exercise frequency 2 WHOQOL-BREF scale 3 Bariatric Quality of Life Questionnaire BQL 4 Three-Factor Eating Questionnaire TFEQ-R18 5 Yale Food Addiction Scale YFAS20 6 Depression Anxiety Stress Scales-21 DASS-21 The investigators hypothesize that the above risk factors are significantly related to each other and failure to weight loss after bariatric surgery The aims are to analyze the risk rate of weight regain by different weight loss treatments that can promote quality of weight management
Another weight loss treatment was bariatric surgery The surgical treatment focuses on morbidity obese patients Decrease food intake and absorb calories by changing the structure of the stomach and intestine to weight loss and improve comorbidities Moreover three functions for bariatric surgery by different mechanisms to weight loss outcome include 1 restriction 2 malabsorption 3 mixed function and which indication for more than 375 BMI and more than 325 BMI with two or more uncontrol obesity-related comorbidities
Since obesity is not a condition that can be cured by surgical removal of lesions forever patients often experience weight loss failure after receiving both medical and surgical treatments Particularly the probability of weight loss failure after medical treatment is higher than that after surgical treatment Complexed risk factors caused failure weight loss from behavioral dietary quality of life remission rate of comorbidities genetic inheritance physical Inactivity and psychological status Moreover failure weight loss has two definitions 1 weight regain WR and 2 insufficient weight loss IWL The investigators searched many studies to organize failure weight loss definitions referenced by Surgery for Obesity and Related Disease SORD in the American Society for Metabolic and Bariatric Surgery ASMBS IWL is defined as less than 50 percent excess weight loss EWL or less than 35 BMI after 18 months WR is defined as 1 more than the nadir weight of 10 kg 2 more than the nadir weight of 25 EWL 3 more than the nadir weight of 5 BMI 4 successfully reduced to a BMI below 35 but after 1-year post-treatment it exceeded BMI 35 5 at any point within 1-year post-treatment the weight is higher than the lowest weight achieved 6 the weight regained is more than 15 of the lowest weight achieved In contrast to weight gain after medicine which is defined by population proportion 5 10 15 20 statistical analysis
The study was an observational cohort study The investigators will use the six types of questionnaires 1 Demographic parameters and exercise frequency 2 WHOQOL-BREF scale 3 Bariatric Quality of Life Questionnaire BQL 4 Three-Factor Eating Questionnaire TFEQ-R18 5 Yale Food Addiction Scale YFAS20 6 Depression Anxiety Stress Scales-21 DASS-21 The investigators hypothesize that the above risk factors are significantly related to each other and failure to weight loss after bariatric surgery The aims are to analyze the risk rate of weight regain by different weight loss treatments that can promote quality of weight management
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None