Ignite Creation Date:
2024-07-17 @ 11:20 AM
Last Modification Date:
2024-10-26 @ 3:34 PM
Study NCT ID:
NCT06496282
Status:
RECRUITING
Last Update Posted:
2024-07-11
First Post:
2024-07-03
Brief Title:
Lemborexant on Improving Sleep Quality Among Hospital Rotating Shift Workers
Sponsor:
Phramongkutklao College of Medicine and Hospital
Organization:
Phramongkutklao College of Medicine and Hospital
Study Overview
Official Title:
The Efficacy of Lemborexant Versus Placebo on Improving Sleep Quality Among Hospital Rotating Shift Workers A Randomized Double-Blind Placebo-Controlled Trial
Status:
RECRUITING
Status Verified Date:
2024-06
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
Shift Work Sleep Disorder SWSD are caused by working shifts with a wake-up schedule and sleeping in a way that is different from the natural way of sleeping and avoiding sleep usually results in deviations of the biological clock Biological clock which is an important cause of sleep problems including insomnia excessive sleepiness or daytime sleepiness these problems was associated cadiovascular events decrease quality of life and long term working At the present there are limited information regarding the effectiveness of medications used to promote sleep in shift workers Lemborexant is specific in binding to orexin type 2 which has a direct effect on sleep and there are limited biomarkers monitoring from the use of lemborexant including still not found Which studies have followed depressive symptoms anxiety symptoms and cognition from a group of people with insomnia the aim of study to assessment effectiveness of lemborexant on sleep efficiency quality of life symptoms of depression cognition BDNF CRP IL-6 and TNF-alpha levels of volunteers working on rotating shifts
Detailed Description:
None
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None