Ignite Creation Date:
2024-07-17 @ 11:15 AM
Last Modification Date:
2024-10-26 @ 3:32 PM
Study NCT ID:
NCT06467448
Status:
NOT_YET_RECRUITING
Last Update Posted:
2024-06-21
First Post:
2024-06-14
Brief Title:
Comparing Train-of-Four Recovery in the Adductor Pollicis Versus the Adductor Digiti Minimi in Elective Surgery Patients
Sponsor:
University of North Carolina Chapel Hill
Organization:
University of North Carolina Chapel Hill
Study Overview
Official Title:
Comparing Train-of-Four Recovery in the Adductor Pollicis Versus the Adductor Digiti Minimi in Elective Surgery Patients Using EMG
Status:
NOT_YET_RECRUITING
Status Verified Date:
2024-06
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
The train-of-four TOF ratio is a quantitative measure used in anesthesia to assess the degree of neuromuscular blockade induced by neuromuscular blocking agents during surgical procedures Current American Society of Anesthesiologists guidelines recommend monitoring the TOF ratio to guide the administration and reversal of NMBAs with a target ratio of 09 or higher at adductor pollicis muscle indicating adequate reversal and restoration of neuromuscular function
This proposed study aims to observe and compare the TOF ratio between two different muscles of the hand adductor pollicis and adductor digiti minim using anesthesia monitors on both of their arms during recovery of neuromuscular function Surgery and anesthesia will occur per standard of care
This proposed study aims to observe and compare the TOF ratio between two different muscles of the hand adductor pollicis and adductor digiti minim using anesthesia monitors on both of their arms during recovery of neuromuscular function Surgery and anesthesia will occur per standard of care
Detailed Description:
The study population will enroll adult patients 18 who will receive non-depolarizing neuromuscular blocking drugs as part of a routine general anesthetic and who will have monitoring of their recovery from neuromuscular block performed using the Tetragraph Senzime Sweden Patients with upper limb weakness neurological deficits and inability to use the other arm to record the second EMG recording will be excluded
Procedures methods
Adult patients undergoing general anesthesia with the use of muscle relaxants will have anesthesia monitors on both of their arms On one arm the study sticky pad will be placed on the forearm and over the base of the little finger On the other arm the standard monitor is placed on the forearm and over the base of the thumb
To identify pre-operative patients an EPIC report will be utilized to screen for eligible participants Patients will be contacted via phone by a research team member the day before their procedure and enrolled Informed consent will be formally obtained on the day of the procedure
Procedures methods
Adult patients undergoing general anesthesia with the use of muscle relaxants will have anesthesia monitors on both of their arms On one arm the study sticky pad will be placed on the forearm and over the base of the little finger On the other arm the standard monitor is placed on the forearm and over the base of the thumb
To identify pre-operative patients an EPIC report will be utilized to screen for eligible participants Patients will be contacted via phone by a research team member the day before their procedure and enrolled Informed consent will be formally obtained on the day of the procedure
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
True
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
False
Is an FDA AA801 Violation?:
None