Ignite Creation Date:
2024-07-17 @ 11:12 AM
Last Modification Date:
2024-10-26 @ 3:32 PM
Study NCT ID:
NCT06468657
Status:
COMPLETED
Last Update Posted:
2024-07-12
First Post:
2024-06-15
Brief Title:
Evaluation of the Impact of Ejection Fraction on Clinical Outcomes in Patients Undergoing Cardiovascular Surgery
Sponsor:
Kanuni Sultan Suleyman Training and Research Hospital
Organization:
Kanuni Sultan Suleyman Training and Research Hospital
Study Overview
Official Title:
Evaluation of the Impact of Ejection Fraction on Clinical Outcomes in Patients Undergoing Cardiovascular Surgery
Status:
COMPLETED
Status Verified Date:
2024-10
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
This study evaluates the impact of ejection fraction EF on clinical outcomes in patients undergoing cardiovascular surgeries specifically coronary artery bypass grafting CABG and heart valve replacement It spans surgeries performed between 2012 and 2022 at Mehmet Akif Ersoy Thoracic and Cardiovascular Surgery Training and Research Hospital Patients are categorized into two groups based on their preoperative EF those with preserved EF 50 and those with reduced EF 50
The primary aim is to assess how EF affects postoperative morbidity mortality hospital stay and complications Secondary aims include evaluating the development of postoperative arrhythmias the need for vasopressors and inotropes and transfusion requirements
Data will be collected retrospectively from hospital records and electronic health systems The studys findings are expected to provide insights into tailored perioperative and postoperative management strategies for patients with varying EF levels ultimately improving clinical outcomes
The primary aim is to assess how EF affects postoperative morbidity mortality hospital stay and complications Secondary aims include evaluating the development of postoperative arrhythmias the need for vasopressors and inotropes and transfusion requirements
Data will be collected retrospectively from hospital records and electronic health systems The studys findings are expected to provide insights into tailored perioperative and postoperative management strategies for patients with varying EF levels ultimately improving clinical outcomes
Detailed Description:
Primary Objective The primary objective of this study is to evaluate the impact of ejection fraction EF on clinical outcomes in patients undergoing cardiovascular surgery Specifically the study aims to analyze the effects of EF on postoperative morbidity and mortality rates length of hospital stay and postoperative complications
Secondary Objectives Secondary objectives include assessing the development of arrhythmias in the postoperative period the need for vasopressors and inotropes and the requirement for transfusions
Scope of the Study Time Frame The study will encompass cardiovascular surgeries performed between 2012 and 2022 This time frame is selected to obtain a sufficient data set and evaluate long-term outcomes
Research Center The study will be conducted at Mehmet Akif Ersoy Thoracic and Cardiovascular Surgery Training and Research Hospital Patient data from cardiovascular surgeries performed at this center will be analyzed
Patient Population The study will include all patients who underwent cardiovascular surgery within the specified time frame and had preoperative ejection fraction EF measurements
Study Design Group Formation
Patients will be divided into two main groups based on their preoperative EF values
Preserved EF Group Patients with an EF of 50 or above Reduced EF Group Patients with an EF below 50 Data to be Examined
The following postoperative data will be examined and compared between the two groups
Development of Postoperative Arrhythmias Whether patients develop arrhythmias in the postoperative period
Vasopressor Requirement The need for vasopressors in the postoperative period Inotrope Requirement Whether patients require inotropic support postoperatively
Transfusion Requirement The need for blood transfusions in the postoperative period
Mortality Survival rates of patients following surgery Need for Revision Surgery Whether patients require additional surgical interventions postoperatively
Length of Stay in ICU Duration of patients stay in the intensive care unit Total Hospital Stay Overall length of hospital stay Data Collection Method Data will be retrospectively collected from hospital records and electronic health record EHR systems
This structured approach aims to comprehensively evaluate the clinical outcomes of patients with varying levels of ejection fraction undergoing major cardiovascular surgeries thereby providing insights that can enhance patient management strategies
Secondary Objectives Secondary objectives include assessing the development of arrhythmias in the postoperative period the need for vasopressors and inotropes and the requirement for transfusions
Scope of the Study Time Frame The study will encompass cardiovascular surgeries performed between 2012 and 2022 This time frame is selected to obtain a sufficient data set and evaluate long-term outcomes
Research Center The study will be conducted at Mehmet Akif Ersoy Thoracic and Cardiovascular Surgery Training and Research Hospital Patient data from cardiovascular surgeries performed at this center will be analyzed
Patient Population The study will include all patients who underwent cardiovascular surgery within the specified time frame and had preoperative ejection fraction EF measurements
Study Design Group Formation
Patients will be divided into two main groups based on their preoperative EF values
Preserved EF Group Patients with an EF of 50 or above Reduced EF Group Patients with an EF below 50 Data to be Examined
The following postoperative data will be examined and compared between the two groups
Development of Postoperative Arrhythmias Whether patients develop arrhythmias in the postoperative period
Vasopressor Requirement The need for vasopressors in the postoperative period Inotrope Requirement Whether patients require inotropic support postoperatively
Transfusion Requirement The need for blood transfusions in the postoperative period
Mortality Survival rates of patients following surgery Need for Revision Surgery Whether patients require additional surgical interventions postoperatively
Length of Stay in ICU Duration of patients stay in the intensive care unit Total Hospital Stay Overall length of hospital stay Data Collection Method Data will be retrospectively collected from hospital records and electronic health record EHR systems
This structured approach aims to comprehensively evaluate the clinical outcomes of patients with varying levels of ejection fraction undergoing major cardiovascular surgeries thereby providing insights that can enhance patient management strategies
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None