Ignite Creation Date:
2024-07-17 @ 11:11 AM
Last Modification Date:
2024-10-26 @ 3:32 PM
Study NCT ID:
NCT06472466
Status:
NOT_YET_RECRUITING
Last Update Posted:
2024-06-25
First Post:
2024-06-07
Brief Title:
Sleep and Eating Behaviours in Adolescents
Sponsor:
University of Padova
Organization:
University of Padova
Study Overview
Official Title:
Healthier and Earlier Through Digital Technology Towards a Transdiagnostic Staging Model of Eating and Sleep Disorders in Adolescence
Status:
NOT_YET_RECRUITING
Status Verified Date:
2024-06
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
SANA
Brief Summary:
Insomnia and eating disorders are highly prevalent among adolescents often co-occur and are associated with somatic and mental comorbidities and functional impairment The first aim of this project is to longitudinally monitor psychological functioning and sleep- and eating-related behaviours in a large sample of students aged 14-17 yrs N 854 to identify the variables that predict transition from a prodromal phase to a clinical stage and signpost individuals at risk or with clinical symptoms to self-help materials and clinical support The second aim is to test whether increased emotional reactivity to disease-related stimuli stimuli related to sleep or eating in a virtual reality environment can discriminate between individuals at risk or with clinical symptoms and healthy peers The third goal is to conduct a pilot randomized controlled trial to test a virtual reality self-help exposure-based intervention to remediate eating or sleep difficulties in individuals at risk or exhibiting clinical symptoms of eating disorders or insomnia
Detailed Description:
The present study aims
1 To measure eating- and sleep-related behaviours and psychological functioning over time 6-9 months in a large sample of secondary school students aged 14 to 17 years old and identify individuals at risk or exhibiting clinical symptoms in order to signpost them to self-help written materials and clinical support
2 To establish whether increased emotional reactivity to disease-related stimuli sleep- or eating-related in a virtual reality environment discriminates between individuals at risk or with clinical levels of eating andor insomnia and healthy peers
3 To conduct a pilot randomized controlled trial to test a virtual reality self-help exposure-based intervention for eating or sleep difficulties targeting increased emotional reactivity to disease-related stimuli
A minimum of 854 adolescents will be recruited and assessed at baseline 3- and 6-to-9 months follow-up
A mobile application has been specifically designed for this study incorporating gamified elements to enhance engagement and adherence The app can be downloaded for free on participants mobile devices and will play a crucial role throughout the study serving multiple purposes It will be first used as an assessment tool participants will complete baseline and follow-up questionnaires Moreover they will receive notifications to collect Ecological Momentary Assessment EMA data Finally it will provide access to self-help written materials on sleep and eating habits and disorders that participants will be able to read and download from the beginning of the study
The sample size was estimated based on the recommendations for sample size calculation in prevalence studies The calculation was performed using the Scalex sample size calculator and was based on four parameters level of confidence which was set at 95 level of precision of the estimated prevalence which was set at 3 the recommended threshold for large scale studies likely to gain attention from policy makers estimated prevalence of the disorder which was established at 20 based on prevalence of sleep and eating problems among Italian adolescents anticipated loss which was set at 20 based on the loss of data at six months in previous studies
Assessment phase
Students whose parents will have given informed consent to participate in the study will complete the baseline assessment through the App and provide information on
gender age family composition and history of mental health disorders
sleep behaviours and insomnia symptoms Insomnia Severity Index ISI Sleep Health Dimensions Questionnaire
eating behaviours and symptoms Screening Tool for Eating Disorders SCOFF Eating Disorder Examination Questionnaire EDE-Q 60
history of weight-based victimization
depression anxiety and stress symptoms Depression Anxiety and Stress Scales DASS-21
strengths and difficulties regarding emotional functioning Cognitive Emotion Regulation Questionnaire CERQ-IS
emotional behavioural and interpersonal difficulties and prosociality Strengths and Difficulties Questionnaire SDQ
social media usage Bergen Social Media Addiction Scale BSMAS
They will also undergo a 4-day EMA to assess sleep and eating behaviours sleepiness eating disorder symptoms and emotional states multiple timesday
At three- and six-to-nine months follow-up participants will complete a subset of measures completed at baseline
Insomnia Severity Index ISI
Eating Disorder Examination Questionnaire EDE-Q 60
Screening Tool for Eating Disorders SCOFF
Depression Anxiety and Stress Scales DASS-21
4-day Ecological Momentary Assessment EMAs
Self-help written materials have been developed by the research team for the purposes of the present study They consist of a short booklet about sleep and eating behaviours and disorders providing strategies to cope with them Contents will be available to participants from the beginning of the study They will be able to both read and download them directly from the application on their mobile devices
Individuals identified as at high-risk for or with insomnia ISI total score min0 max28 cut-off 8 for high-risk individuals cut-off15 for clinical levels of insomniaeating disorder symptoms SCOFF total score min1 max5 cut-off 3 at baseline and at 3 months will be invited to take part in a 15-min virtual reality exposure session to measure emotional reactivity to eating andor sleep-related stimuli Individuals at high-risk forwith insomnia will be exposed to a virtual bedroom while individuals at high-risk forwith eating disorders will be exposed to a virtual kitchen A control group with no symptoms of eating disorders or insomnia will also be recruited and exposed to both the virtual bedroom and virtual kitchen in randomized order
Intervention phase Participants in the high-riskclinical group approximately N100 will be randomly allocated to an intervention or a control condition Those in the intervention condition will be asked to use the virtual reality scenario for a week at home with the aim of reducing emotional reactivity associated with sleep or eating-related stimuli Those in the control condition will only have received access to the self-help written materials Visual analogue scales will be presented to evaluate anxiety levels before and after the exposure Feasibility and acceptability of the virtual reality environments will be assessed through visual analogue scales and a qualitative interview Participants across groups will also complete EMAs of eating andor sleep behaviours during the week
1 To measure eating- and sleep-related behaviours and psychological functioning over time 6-9 months in a large sample of secondary school students aged 14 to 17 years old and identify individuals at risk or exhibiting clinical symptoms in order to signpost them to self-help written materials and clinical support
2 To establish whether increased emotional reactivity to disease-related stimuli sleep- or eating-related in a virtual reality environment discriminates between individuals at risk or with clinical levels of eating andor insomnia and healthy peers
3 To conduct a pilot randomized controlled trial to test a virtual reality self-help exposure-based intervention for eating or sleep difficulties targeting increased emotional reactivity to disease-related stimuli
A minimum of 854 adolescents will be recruited and assessed at baseline 3- and 6-to-9 months follow-up
A mobile application has been specifically designed for this study incorporating gamified elements to enhance engagement and adherence The app can be downloaded for free on participants mobile devices and will play a crucial role throughout the study serving multiple purposes It will be first used as an assessment tool participants will complete baseline and follow-up questionnaires Moreover they will receive notifications to collect Ecological Momentary Assessment EMA data Finally it will provide access to self-help written materials on sleep and eating habits and disorders that participants will be able to read and download from the beginning of the study
The sample size was estimated based on the recommendations for sample size calculation in prevalence studies The calculation was performed using the Scalex sample size calculator and was based on four parameters level of confidence which was set at 95 level of precision of the estimated prevalence which was set at 3 the recommended threshold for large scale studies likely to gain attention from policy makers estimated prevalence of the disorder which was established at 20 based on prevalence of sleep and eating problems among Italian adolescents anticipated loss which was set at 20 based on the loss of data at six months in previous studies
Assessment phase
Students whose parents will have given informed consent to participate in the study will complete the baseline assessment through the App and provide information on
gender age family composition and history of mental health disorders
sleep behaviours and insomnia symptoms Insomnia Severity Index ISI Sleep Health Dimensions Questionnaire
eating behaviours and symptoms Screening Tool for Eating Disorders SCOFF Eating Disorder Examination Questionnaire EDE-Q 60
history of weight-based victimization
depression anxiety and stress symptoms Depression Anxiety and Stress Scales DASS-21
strengths and difficulties regarding emotional functioning Cognitive Emotion Regulation Questionnaire CERQ-IS
emotional behavioural and interpersonal difficulties and prosociality Strengths and Difficulties Questionnaire SDQ
social media usage Bergen Social Media Addiction Scale BSMAS
They will also undergo a 4-day EMA to assess sleep and eating behaviours sleepiness eating disorder symptoms and emotional states multiple timesday
At three- and six-to-nine months follow-up participants will complete a subset of measures completed at baseline
Insomnia Severity Index ISI
Eating Disorder Examination Questionnaire EDE-Q 60
Screening Tool for Eating Disorders SCOFF
Depression Anxiety and Stress Scales DASS-21
4-day Ecological Momentary Assessment EMAs
Self-help written materials have been developed by the research team for the purposes of the present study They consist of a short booklet about sleep and eating behaviours and disorders providing strategies to cope with them Contents will be available to participants from the beginning of the study They will be able to both read and download them directly from the application on their mobile devices
Individuals identified as at high-risk for or with insomnia ISI total score min0 max28 cut-off 8 for high-risk individuals cut-off15 for clinical levels of insomniaeating disorder symptoms SCOFF total score min1 max5 cut-off 3 at baseline and at 3 months will be invited to take part in a 15-min virtual reality exposure session to measure emotional reactivity to eating andor sleep-related stimuli Individuals at high-risk forwith insomnia will be exposed to a virtual bedroom while individuals at high-risk forwith eating disorders will be exposed to a virtual kitchen A control group with no symptoms of eating disorders or insomnia will also be recruited and exposed to both the virtual bedroom and virtual kitchen in randomized order
Intervention phase Participants in the high-riskclinical group approximately N100 will be randomly allocated to an intervention or a control condition Those in the intervention condition will be asked to use the virtual reality scenario for a week at home with the aim of reducing emotional reactivity associated with sleep or eating-related stimuli Those in the control condition will only have received access to the self-help written materials Visual analogue scales will be presented to evaluate anxiety levels before and after the exposure Feasibility and acceptability of the virtual reality environments will be assessed through visual analogue scales and a qualitative interview Participants across groups will also complete EMAs of eating andor sleep behaviours during the week
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None