Ignite Creation Date:
2024-07-17 @ 11:02 AM
Last Modification Date:
2024-10-26 @ 3:32 PM
Study NCT ID:
NCT06463938
Status:
RECRUITING
Last Update Posted:
2024-06-18
First Post:
2024-06-11
Brief Title:
A Clinical Trial to Compare Lasotronix Alone or in Combination With CPP-ACP to Treat DH
Sponsor:
Dow University of Health Sciences
Organization:
Dow University of Health Sciences
Study Overview
Official Title:
A Clinical Study to Evaluate the Effectiveness of Casein Phosphopeptide Amorphous Calcium Phosphate Paste CPP-ACP Used Alone or in Combination With Lasotronix Diode Laser to Treat Dentin Hypersensitivity
Status:
RECRUITING
Status Verified Date:
2024-07
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
Dentin hypersensitivity DH is defined as sharp pain of a shorter duration arise from exposed dentin in response to several chemicals and thermal or tactile stimuli that cannot be ascribed to other dental defects DH has a prevalence rate ranging from 13 to 921 commonly affecting old ages The use of laser has opened new dimensions in the treatment of DH To the authors knowledge not much research work has been conducted using LASOTRONIX as a treatment modality with CPP-ACP Therefore this research aims to determine the effectiveness of Casein phospho peptide paste CPP-ACP used alone or combined with a diode laser LASOTRONIX
Detailed Description:
DH has a prevalence rate ranging from 13 to 921 commonly affecting old ages and the frequency of DH in patients suffering from periodontal disease is 3-57 Pakistan has reported prevalence from different cities with 364 from Karachi and 22 from Lahore
The use of laser has opened new dimensions in the treatment of DH Theories that support laser therapy explain that irradiation blocks the pain in dentinal tubules by melting and recrystallization of dentin or by tertiary dentine production or evaporation of dentinal fluid Considering the oral soft tissues which contain high amounts of water Lasotronix SMARTm laser diodes have been carefully designed to show their high transmission The 635nm wavelength is optimal for activating tolonium chloride dye for photo-activated chemo therapy eliminating all bacteria and biofilms without any side effects 200 mW power provides safe cold bio stimulation and photo disinfection within a reasonably short therapy time Application of Sodium fluoride NaF has also been indicated for hypersensitivity pains Its application in the form of gel occludes the tubule by calcium fluoride precipitation Agents like potassium nitrate also have promising effects which increase the concentration of potassium ions in nerve endings and alter the nerve action potential in conducting the sensory stimuli
Recently DH treatment has been conducted with different types of laser with different wavelengths either alone or in combination with desensitizing agents and varnishes and has revealed effective results To the authors knowledge not much research work has been conducted using LASOTRONIX as a treatment modality with CPP-ACP Therefore this research aims to determine the effectiveness of Casein phospho peptide paste CPP-ACP used alone or combined with a diode laser LASOTRONIX
The use of laser has opened new dimensions in the treatment of DH Theories that support laser therapy explain that irradiation blocks the pain in dentinal tubules by melting and recrystallization of dentin or by tertiary dentine production or evaporation of dentinal fluid Considering the oral soft tissues which contain high amounts of water Lasotronix SMARTm laser diodes have been carefully designed to show their high transmission The 635nm wavelength is optimal for activating tolonium chloride dye for photo-activated chemo therapy eliminating all bacteria and biofilms without any side effects 200 mW power provides safe cold bio stimulation and photo disinfection within a reasonably short therapy time Application of Sodium fluoride NaF has also been indicated for hypersensitivity pains Its application in the form of gel occludes the tubule by calcium fluoride precipitation Agents like potassium nitrate also have promising effects which increase the concentration of potassium ions in nerve endings and alter the nerve action potential in conducting the sensory stimuli
Recently DH treatment has been conducted with different types of laser with different wavelengths either alone or in combination with desensitizing agents and varnishes and has revealed effective results To the authors knowledge not much research work has been conducted using LASOTRONIX as a treatment modality with CPP-ACP Therefore this research aims to determine the effectiveness of Casein phospho peptide paste CPP-ACP used alone or combined with a diode laser LASOTRONIX
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None