Ignite Creation Date:
2024-07-17 @ 10:58 AM
Last Modification Date:
2024-10-26 @ 3:33 PM
Study NCT ID:
NCT06481449
Status:
RECRUITING
Last Update Posted:
2024-07-01
First Post:
2024-06-22
Brief Title:
Definitive Radiotherapy for Cervical and Upper Thoracic Esophageal Cancer ChCUES A Multi-center Real World Study
Sponsor:
Hebei Medical University Fourth Hospital
Organization:
Hebei Medical University Fourth Hospital
Study Overview
Official Title:
Definitive Radiotherapy for Cervical and Upper Thoracic Esophageal Cancer ChCUES A Multi-center Real World Study
Status:
RECRUITING
Status Verified Date:
2024-06
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
Cervical and upper thoracic esophageal cancer ESCA presents treatment challenges due to limited clinical evidence This multi-center study ChCUES explores radical radiochemotherapy efficacy and safety
Detailed Description:
Cervical and upper thoracic esophageal cancer ESCA are relatively rare diseases presenting treatment challenges due to limited clinical evidence This multi-center study ChCUES explores radical radiotherapy efficacy and safety especially focusing on radiation dose This study collected all eligible patients diagnosed with cervical and upper thoracic ESCA from 6 medical centers Tianjin Cancer Hospital Cancer Hospital of the Chinese Academy of Medical Sciences Fujian Cancer Hospital Fudan University Shanghai Cancer Center Shandong Cancer Hospital and the Fourth Hospital of Hebei Medical University in China Patients were categoried into two group low dose radiation group and high dose radiation group based on radiation dose Basic clinical information including age gender ECOG score pathological type smoking and drinking history initial visit date radiotherapy dose radiotherapy method concurrent chemotherapy modality immunotherapy targeted drug usage treatment efficacy assessment toxicity and side effects and survival time was collected Kaplan-Meier method was used to calculate OS survival differences were assessed using the log-rank test Univariate analysis was conducted via Cox regression modeling with variables demonstrating P values 01 being included in multivariate analysis A significance level of two-sided P 005 was considered statistically significant The aim of this study was to compared the overall survival time between low dose radiation group and high dose radiation dose group and compared the underlying side effects
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None