Ignite Creation Date:
2024-07-17 @ 10:53 AM
Last Modification Date:
2024-10-26 @ 3:34 PM
Study NCT ID:
NCT06492044
Status:
RECRUITING
Last Update Posted:
2024-07-10
First Post:
2024-06-18
Brief Title:
Evaluation of the Association Between Right Atrial Reservoir Strain Variation and Fluid Responsiveness in Patients With Septic Shock
Sponsor:
Centre Hospitalier Universitaire Amiens
Organization:
Centre Hospitalier Universitaire Amiens
Study Overview
Official Title:
Evaluation of the Association Between Right Atrial Reservoir Strain Variation and Fluid Responsiveness in Patients With Septic Shock
Status:
RECRUITING
Status Verified Date:
2024-06
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
RAS-FR
Brief Summary:
Evaluating preload dependence is crucial for managing fluid administration in septic shock patients To avoid unnecessary fluid administration its recommended to use dynamic tests like the passive leg raising PLR maneuver or a fluid challenge FC to see if a patients cardiac output will increase after fluid resuscitation Transthoracic echocardiography TTE is preferred for this because it can non-invasively reliably and reproducibly measure the increase in cardiac output A patient is considered a responder if their stroke volume SV increases by more than 15 after an FC Two-dimensional 2D right atrial strain RAS is a promising tool for evaluating right atrial function According to the Frank-Starling law measuring changes in the RA reservoir strain phase RASr can identify acute changes in preload like those induced by a PLR maneuver or an FC
The aims of this study are to assess the ability of RASr to identify responders after a fluid challenge FC and to evaluate the ability of RASr variation induced by a PLR maneuver to distinguish responders from non-responders to volume expansion
The aims of this study are to assess the ability of RASr to identify responders after a fluid challenge FC and to evaluate the ability of RASr variation induced by a PLR maneuver to distinguish responders from non-responders to volume expansion
Detailed Description:
None
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None