Ignite Creation Date:
2024-07-17 @ 10:51 AM
Last Modification Date:
2024-10-26 @ 3:32 PM
Study NCT ID:
NCT06464445
Status:
RECRUITING
Last Update Posted:
2024-06-25
First Post:
2024-06-12
Brief Title:
Optimization of iTBS for Depression
Sponsor:
Université de Sherbrooke
Organization:
Université de Sherbrooke
Study Overview
Official Title:
Defining Parameters to Optimize Neurostimulation for the Treatment of Pediatric Depression
Status:
RECRUITING
Status Verified Date:
2024-08
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
Repetitive TMS rTMS is a well-established method for modulating brain activity Through successive stimulations in the form of magnetic fields it is possible to modify the sensitivity of neurons in the brain also known as cortical excitability Cortical excitability is important for the induction of brain plasticity the ability of the brain to reorganize itself and form new connections in response to stimuli A particular class of rTMS intermittent theta burst TMS iTBS is commonly used to modulate cortical excitability and induce plasticity for therapeutic purposes notably for treatment-resistant depression
Different iTBS stimulation parameters can be used to induce plasticity This study will focus on two parameters namely the form and duration of the electromagnetic stimulation The shape of the electromagnetic pulse refers to how the electromagnetic wave is configured over time while the duration is simply the period during which this electromagnetic pulse remains active These parameters are expected to influence the effectiveness of iTBS in modulating cortical activity but remain little studied
The main aim of this study will be to compare the effectiveness of different stimulation parameters in the induction of plasticity which will then make it possible to improve the rTMS protocols used for treatment-resistant depression
Different iTBS stimulation parameters can be used to induce plasticity This study will focus on two parameters namely the form and duration of the electromagnetic stimulation The shape of the electromagnetic pulse refers to how the electromagnetic wave is configured over time while the duration is simply the period during which this electromagnetic pulse remains active These parameters are expected to influence the effectiveness of iTBS in modulating cortical activity but remain little studied
The main aim of this study will be to compare the effectiveness of different stimulation parameters in the induction of plasticity which will then make it possible to improve the rTMS protocols used for treatment-resistant depression
Detailed Description:
None
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None