Ignite Creation Date:
2024-07-17 @ 10:41 AM
Last Modification Date:
2024-10-26 @ 3:32 PM
Study NCT ID:
NCT06469892
Status:
COMPLETED
Last Update Posted:
2024-06-24
First Post:
2024-06-14
Brief Title:
Saliva and Plasma Exosomes for Oral Leukoplakia Malignant Transformation Diagnosis and Oral Cancer Prognosis Monitoring
Sponsor:
Beijing Stomatological Hospital Capital Medical University
Organization:
Beijing Stomatological Hospital Capital Medical University
Study Overview
Official Title:
Application of Salivary and Plasma Exosomes in the Diagnosis of Oral Leukoplakia Malignant Transformation and Prognosis Monitoring of Oral Cancer
Status:
COMPLETED
Status Verified Date:
2024-06
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
The goal of this observational study is to test the expression levels of salivary and plasma exosomal miR-185 in patients with oral leukoplakia and oral squamous cell carcinoma The main questions it aims to answer are
Is it possible to identify the cancer risk of oral leukoplakia in its early stages by detecting salivary and plasma exosomal miR-185
Is it possible to monitor the cancer risk of oral leukoplakia and the prognosis of oral cancer using salivary exosomal miR-185
Participants will be asked to
Cooperate with the investigators in completing the oral examination
Take saliva and plasma before the biopsy surgery
Perform the biopsy surgery following the usual diagnostic procedures
Attend regular follow-up appointments every 3 months for the duration of the study
Is it possible to identify the cancer risk of oral leukoplakia in its early stages by detecting salivary and plasma exosomal miR-185
Is it possible to monitor the cancer risk of oral leukoplakia and the prognosis of oral cancer using salivary exosomal miR-185
Participants will be asked to
Cooperate with the investigators in completing the oral examination
Take saliva and plasma before the biopsy surgery
Perform the biopsy surgery following the usual diagnostic procedures
Attend regular follow-up appointments every 3 months for the duration of the study
Detailed Description:
The first part of the study is a cross-sectional study in which the investigators will detect the expression level of salivary exosomal miR-185 in the participants at a single time point The second part of the study is a prospective cohort study in which the investigators will conduct regular follow-ups on the participants enrolled in the first part
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None
Secondary IDs
| Secondary ID | Type | Domain | Link |
|---|---|---|---|
| Z191100006619042 | OTHER_GRANT | None | None |