Ignite Creation Date:
2024-06-16 @ 11:52 AM
Last Modification Date:
2024-10-26 @ 3:32 PM
Study NCT ID:
NCT06460519
Status:
RECRUITING
Last Update Posted:
2024-06-14
First Post:
2024-06-11
Brief Title:
The Prevalence of the Aortic to Radial Pressure Gradient in States of Shock Outside the Context of Cardiac Surgery a Prospective Study
Sponsor:
Hospices Civils de Lyon
Organization:
Hospices Civils de Lyon
Study Overview
Official Title:
Prevalence of the Aortic to Radial Pressure Gradient in States of Shock
Status:
RECRUITING
Status Verified Date:
2024-10
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
PARECHOC
Brief Summary:
First described in cardiac surgery the aortic to radial pressure gradient ATRAP is the cause of an underestimation of the aortic pressure with a measure assumed with a radial catheter and he can concert 1 of 3rd patients The risks factor well known are small height previous hypertension long and difficult surgery radial artery diameter less than 18mm
The ATRAP definition is a pressure difference between radial and femoral same of the aortic pressure pressure of 25mmHg on the systolic pressure or a pressure difference on the mean pressure of 10mmHg both measures realised by arterial canulation and with a duration superior than 5 minutes
If this gradient appears in pathophysiological specifics situations there is a risk of inappropriate administration of vasopressors with more hospitalisation days more side effect of vasopressors like an augmentation of myocardial work
The ATRAP is documented in septic shock with a prevalence between 21 and 27 The ATRAP can appear in shocks moreover with doses of equivalent norepinephrine of 05 µgkgmin who is use for the definition of refractive shock the difference between the two pressure is higher if the dose of equivalent norepinephrine is higher than 1µgkgmin But the prevalence and risks factors are barely unknowns in this situation
Most of the time a radial arterial catheter is used for hemodynamic monitoring for his simplicity of utilisation and the lows complications associated Some medical teams in cardiac surgeries or in intensive care unit ICU for the management of shocks used often radial and femoral arterial catheter It seems there is no at risk for the utilisation of a radial and femoral arterial canulation
Out of the situation of cardiac surgery there is a lack of information of the ATRAP the objective of the study is to evaluate the prevalence of the ATRAP in shock out of the situation of cardiac surgery
The ATRAP definition is a pressure difference between radial and femoral same of the aortic pressure pressure of 25mmHg on the systolic pressure or a pressure difference on the mean pressure of 10mmHg both measures realised by arterial canulation and with a duration superior than 5 minutes
If this gradient appears in pathophysiological specifics situations there is a risk of inappropriate administration of vasopressors with more hospitalisation days more side effect of vasopressors like an augmentation of myocardial work
The ATRAP is documented in septic shock with a prevalence between 21 and 27 The ATRAP can appear in shocks moreover with doses of equivalent norepinephrine of 05 µgkgmin who is use for the definition of refractive shock the difference between the two pressure is higher if the dose of equivalent norepinephrine is higher than 1µgkgmin But the prevalence and risks factors are barely unknowns in this situation
Most of the time a radial arterial catheter is used for hemodynamic monitoring for his simplicity of utilisation and the lows complications associated Some medical teams in cardiac surgeries or in intensive care unit ICU for the management of shocks used often radial and femoral arterial catheter It seems there is no at risk for the utilisation of a radial and femoral arterial canulation
Out of the situation of cardiac surgery there is a lack of information of the ATRAP the objective of the study is to evaluate the prevalence of the ATRAP in shock out of the situation of cardiac surgery
Detailed Description:
None
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None