Ignite Creation Date:
2024-06-16 @ 11:52 AM
Last Modification Date:
2024-10-26 @ 3:32 PM
Study NCT ID:
NCT06460168
Status:
NOT_YET_RECRUITING
Last Update Posted:
2024-07-10
First Post:
2024-06-11
Brief Title:
Mulligan and Maitland Techniques in Post PRP Knee Osteoarthritis
Sponsor:
Riphah International University
Organization:
Riphah International University
Study Overview
Official Title:
Comparative Effects of Mulligan and Maitland Techniques on Pain Range of Motion and Functional Disability in Post Prp Knee Osteoarthritis
Status:
NOT_YET_RECRUITING
Status Verified Date:
2024-07
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
Knee osteoarthritis OA is a major cause of disability nowadays Osteoarthritis OA also known as degenerative joint disease is typically the result of wear and tear and progressive loss of articular cartilage It is most common in elderly people and can be divided into two types primary and secondary Platelet-rich plasma PRP is an autologous blood product that contains a high concentration of platelets specifically 3 to 5 times that of normal blood PRP contains a high concentration of autogenous growth factors including vascular endothelial growth factor platelet-derived growth factor and transforming growth factor-β which promote the proliferation of chondrocytes and the synthesis of the extracellular matrix PRP is increasingly being used in the field of sports injury because of its simple preparation method low cost and high degree of safety A randomized clinical trial will be conducted at Ibne Sina HospitalMultan Non probability convenience sampling technique will be applied to enroll patients who will be allocated through computerized randomization into group A group B to collect data Sample size will be 36 This will be allocated to three groups through lottery method Group A will be given MWM and group B will be given Maitland techniques while Group C will receive only baseline treatment The study will be completed within the time duration of ten months Primary Outcome measures of the research will be Pain Range of motion functional status Data will be analyzed using SPSS software version 25 After assessing normality of data by Shapiro-wilk test it will be decided either parametric or non-parametric test will be used within a group or between two groups
Detailed Description:
A study conducted since 2022 evaluated the comparative effects of muscle energy and mobilization with movement techniques for knee pain Range of motion and functional disability in patients with knee OsteoarthritisA randomized clinical trial was conducted at Physiotherapy Department of Bakhtawar Amin College of Rehabilitation Sciences Multan Patients of age 40-60 years with active pain for more than 3 months diagnosed with Grade I II and III of knee osteoarthritis by orthopedic surgeon according to Kellgren and Lawrence Scale and on basis of radiograph were included Patients with knee osteoarthritis of grade IV history of fracture dislocation or radiating pain were excluded Sixty-eight 68 patients were equally divided in two groups Mulligan group and METs group Pain intensity was 019 p001 WOMAC score was 0007p001 Knee flexion was 0110P0995 and Knee extension deficit score was 0087 P0998 Coefficient alpha for with in group subject effect for pain functional disability and knee flexion and extension deficit is P005 Both techniques post isometric relaxation technique of METs and mobilization with movement technique of Mulligans significantly reduced pain functional disability and symptoms
Since 2022 conducted a study to find out find whether neuromuscular stimulation of vastus medialis oblique VMO in combination with Maitlands mobilization and exercises was more effective as compared to Maitlands mobilization with exercises alone in patients with knee OA Sixty patients with knee OA were purposively selected and randomly distributed to two groups that received an intervention for eight weeks Group A patients received Maitlands mobilization in combination with exercises and group B patients received the same intervention as group A in combination with neuromuscular stimulation of VMO muscle Both groups showed significant P005 within-group improvement in the knee pain levels and stiffness as reflected by NPRS and WOMAC index
Another study conducted in 2020 investigate the effectiveness of Mulligans mobilization with movement MWM and Myofascial release on pain range of motion and functional abilities in patients with knee osteoarthritis A purposive sample of 30 patients from two major hospitals of Faisalabad was randomly divided into two treatment groups Group A received Mulligans MWM and group B received Myofascial release Electrotherapy and exercise program was the same for both groups The interventional program was of two weeks five days a week once a day lease were effective for knee osteoarthritis in terms of pain range of motion and for functional abilities However Mulligans MWM produced more quick outcomes than Myofascial release
One study conducted in 2019 study is to determine the outcome and efficacy of Mulligans mobilization with movement MWM with Maitland mobilization along with conventional therapy in the patients with knee osteoarthritis OA randomized controlled trial study was performed at the Department of Physiotherapy Mayo Hospital Lahore Pakistan Sixty-two patients were selected for the study MWM was introduced in half of the patients and Maitland mobilizations in the second half for 2 weeks
Since 2022 conducted a study to find out find whether neuromuscular stimulation of vastus medialis oblique VMO in combination with Maitlands mobilization and exercises was more effective as compared to Maitlands mobilization with exercises alone in patients with knee OA Sixty patients with knee OA were purposively selected and randomly distributed to two groups that received an intervention for eight weeks Group A patients received Maitlands mobilization in combination with exercises and group B patients received the same intervention as group A in combination with neuromuscular stimulation of VMO muscle Both groups showed significant P005 within-group improvement in the knee pain levels and stiffness as reflected by NPRS and WOMAC index
Another study conducted in 2020 investigate the effectiveness of Mulligans mobilization with movement MWM and Myofascial release on pain range of motion and functional abilities in patients with knee osteoarthritis A purposive sample of 30 patients from two major hospitals of Faisalabad was randomly divided into two treatment groups Group A received Mulligans MWM and group B received Myofascial release Electrotherapy and exercise program was the same for both groups The interventional program was of two weeks five days a week once a day lease were effective for knee osteoarthritis in terms of pain range of motion and for functional abilities However Mulligans MWM produced more quick outcomes than Myofascial release
One study conducted in 2019 study is to determine the outcome and efficacy of Mulligans mobilization with movement MWM with Maitland mobilization along with conventional therapy in the patients with knee osteoarthritis OA randomized controlled trial study was performed at the Department of Physiotherapy Mayo Hospital Lahore Pakistan Sixty-two patients were selected for the study MWM was introduced in half of the patients and Maitland mobilizations in the second half for 2 weeks
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None