Ignite Creation Date:
2024-06-16 @ 11:52 AM
Last Modification Date:
2024-10-26 @ 3:32 PM
Study NCT ID:
NCT06456281
Status:
RECRUITING
Last Update Posted:
2024-07-01
First Post:
2024-06-07
Brief Title:
Multi-omics Model for Pancreatic Cancer Screening Using cfDNA
Sponsor:
Fudan University
Organization:
Fudan University
Study Overview
Official Title:
Development and Validation of Multi-omics Model for Screening of Pancreatic Cancer Using cfDNA
Status:
RECRUITING
Status Verified Date:
2024-06
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
This is a prospective case-control study aiming at developing a cell free DNA cfDNA multi-omics precise diagnostic model for screening of pancreatic cancer
Detailed Description:
Peripheral blood samples from participants with new diagnosis of pancreatic cancers precancerous lesions and healthy individuals will be collected to characterize the cancer-specific signatures by low-pass whole-genome sequencing and target methylation sequencing using cfDNA An ensemble multi-omics model will be trained aided by machine learning algorithm and validated in test set The performance of this multi-omics model distinguishing pancreatic cancer from non-cancer will be evaluated
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None