Ignite Creation Date:
2024-06-16 @ 11:52 AM
Last Modification Date:
2024-10-26 @ 3:32 PM
Study NCT ID:
NCT06459115
Status:
RECRUITING
Last Update Posted:
2024-06-20
First Post:
2024-06-10
Brief Title:
Adherence to Medication in Patients With Acute Decompensated Heart Failure
Sponsor:
Universität des Saarlandes
Organization:
Universität des Saarlandes
Study Overview
Official Title:
Adherence to Medication in Patients With Acute Decompensated Heart Failure a Cross-sectional Study at the Emergency Department ADHF-ED Adherence to Medication in Patients With Acute Decompensated Heart Failure at the Emergency Department
Status:
RECRUITING
Status Verified Date:
2024-06
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
ADHF-ED
Brief Summary:
Every day patients present to emergency department due to acute heart failure There are many causes for decompensation One possible cause is a lack of adherence to heart failure medication prognosis-improving medications and diuretics The aim of this study is to directly measure adherence in patients with acute heart failure gold standard of adherence measurement using liquid chromatography coupled to high-resolution mass spectrometry LC-HRMSMS at the emergency department Questionnaires are used to investigate possible factors influencing adherence
Detailed Description:
Several drugs has been shown to improve survival and to reduce the risk for hospitalization for acute heart failure AHF in patients with chronic heart failure
Despite optimal drug treatment patients with heart failure suffer one hospitalization for AHF every year on average with the requirement of intravenous diuretics Hence AHF is one of the leading causes for emergency department visits in elderly patients
A possible cause for AHF in patients with known heart failure is nonadherence to drug treatment Long-term-adherence to drugs of chronic diseases is low Direct methods to assess adherence like the measurement drug levels or metabolites in body fluids are considered as the gold standard
This study aimed to i provide direct measured adherence rates of patients presented with AHF to the emergency department and ii to identify patient-related factors with impact on adherence
Despite optimal drug treatment patients with heart failure suffer one hospitalization for AHF every year on average with the requirement of intravenous diuretics Hence AHF is one of the leading causes for emergency department visits in elderly patients
A possible cause for AHF in patients with known heart failure is nonadherence to drug treatment Long-term-adherence to drugs of chronic diseases is low Direct methods to assess adherence like the measurement drug levels or metabolites in body fluids are considered as the gold standard
This study aimed to i provide direct measured adherence rates of patients presented with AHF to the emergency department and ii to identify patient-related factors with impact on adherence
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None