Ignite Creation Date:
2024-06-16 @ 11:52 AM
Last Modification Date:
2024-10-26 @ 3:31 PM
Study NCT ID:
NCT06452823
Status:
ENROLLING_BY_INVITATION
Last Update Posted:
2024-06-11
First Post:
2024-06-05
Brief Title:
Efficacy and Safety of Catheter Ablation of Atrial Fibrillation in Patients With Thyroid Hormone Stabilization
Sponsor:
The Second Affiliated Hospital of Jiaxing University
Organization:
The Second Affiliated Hospital of Jiaxing University
Study Overview
Official Title:
Cardiovascular Medicine Department of Second Affiliated Hospital of Jiaxing University
Status:
ENROLLING_BY_INVITATION
Status Verified Date:
2024-06
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
SQUIRREL
Brief Summary:
Patients with hyperthyroidism or hypothyroidism are often combined with atrial fibrillation but after the stabilization of thyroid hormone levels after treatment the patients atrial fibrillation still persists Radiofrequency ablation of the atrial fibrillation as one of the treatment options for atrial fibrillation has been widely used in the clinic and has significant efficacy in maintaining sinus rhythm improving cardiac function and improving the prognosis of patients However there is a lack of clinical monitoring data on radiofrequency ablation of atrial fibrillation in patients who have combined thyroid dysfunction and have stabilized their thyroid hormone levels after treatment
Detailed Description:
In patients recommended by guidelines for atrial catheter radiofrequency ablation of atrial fibrillation catheter radiofrequency ablation was performed after exclusion of contraindications and was observed and compared between patients with comorbid pre-existing thyroid hormone disorders and patients without comorbid atrial fibrillation after radiofrequency ablation1 time to sexual rhythm maintenance incidence of cardiac-related complications and incidence of noncardiac-related complications within 3 months and 1 year2 walking distance on a six-minute walk test within 3 months1 year comparison of percent left ventricular ejection fraction and comparison of left ventricular diastolic diameter at the time 3 months1 yearTo comprehensively assess the efficacy and safety of catheterized radiofrequency ablation of atrial fibrillation in patients with comorbidities of prior thyroid hormone disorders
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None