Ignite Creation Date:
2024-06-16 @ 11:51 AM
Last Modification Date:
2024-10-26 @ 3:31 PM
Study NCT ID:
NCT06450691
Status:
NOT_YET_RECRUITING
Last Update Posted:
2024-07-03
First Post:
2024-06-05
Brief Title:
Modeling Amyotrophic Lateral Sclerosis With Fibroblasts
Sponsor:
Assistance Publique - Hôpitaux de Paris
Organization:
Assistance Publique - Hôpitaux de Paris
Study Overview
Official Title:
Modeling of Amyotrophic Lateral Sclerosis Using Patient Fibroblasts to Study Different Form of the Disease
Status:
NOT_YET_RECRUITING
Status Verified Date:
2024-06
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
FIBRALS
Brief Summary:
Amyotrophic Lateral Sclerosis ALS is the most common motor neuron disease in adults This longitudinal study involves three cohorts of participants patients with sporadic or hereditary ALS asymptomatic individuals carrying pathogenic mutations responsible for ALS and control subjects In this study a skin biopsy and blood sampling will be performed at the initial visit M0 then at M12 - 2 months for patients and at M36 - 12 months for asymptomatic carriers of pathogenic mutations The aim of this research is to model ALS pathology using fibroblasts derived from the patients skin biopsies
Detailed Description:
Amyotrophic Lateral Sclerosis ALS is the most common motor neuron disease in adults This longitudinal study involves three cohorts of participants patients with sporadic or hereditary ALS asymptomatic individuals carrying pathogenic mutations responsible for ALS and control subjects In this study a skin biopsy and blood sampling will be performed at the initial visit M0 then at M12 - 2 months for patients and at M36 - 12 months for asymptomatic carriers of pathogenic mutations The aim of this research is to model ALS pathology using fibroblasts derived from the patients skin biopsies
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None