Ignite Creation Date:
2024-06-16 @ 11:51 AM
Last Modification Date:
2024-10-26 @ 3:32 PM
Study NCT ID:
NCT06457646
Status:
NOT_YET_RECRUITING
Last Update Posted:
2024-06-13
First Post:
2024-06-01
Brief Title:
mRNA Expression and Genetic Polymorphisms Affecting DRD3 rs6280 and HTR2A rs6313 in Bruxism
Sponsor:
University of Monastir
Organization:
University of Monastir
Study Overview
Official Title:
mRNA Expression and Genetic Polymorphisms Affecting DRD3 rs6280 and HTR2A rs6313 in Bruxism
Status:
NOT_YET_RECRUITING
Status Verified Date:
2024-06
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
The goal of this observational study is to learn about the genetic factors influencing bruxism a condition characterized by teeth grinding in a group of participants The main questions it aims to answer are
Is there a significant association between the rs6313 polymorphism of the HTR2A gene and bruxism
Is there a significant association between the rs6280 polymorphism of the DRD3 gene and bruxism
Participants will
Provide DNA samples for genotyping of the DRD3 rs6280 and HTR2A rs6313 polymorphisms
Provide RNA samples to assess changes in the expression of HTR2A and DRD3 Researchers will compare the genetic data and RNA expression levels between individuals with bruxism and those without controls to see if there are significant genetic differences and expression changes associated with bruxism
Is there a significant association between the rs6313 polymorphism of the HTR2A gene and bruxism
Is there a significant association between the rs6280 polymorphism of the DRD3 gene and bruxism
Participants will
Provide DNA samples for genotyping of the DRD3 rs6280 and HTR2A rs6313 polymorphisms
Provide RNA samples to assess changes in the expression of HTR2A and DRD3 Researchers will compare the genetic data and RNA expression levels between individuals with bruxism and those without controls to see if there are significant genetic differences and expression changes associated with bruxism
Detailed Description:
None
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
True
Is an Unapproved Device?:
True
Is a PPSD?:
None
Is a US Export?:
False
Is an FDA AA801 Violation?:
None
Secondary IDs
| Secondary ID | Type | Domain | Link |
|---|---|---|---|
| 0000-0002-5945-7764 | OTHER | 0000-0002-5945-7764 | None |