Ignite Creation Date:
2024-06-16 @ 11:51 AM
Last Modification Date:
2024-10-26 @ 3:32 PM
Study NCT ID:
NCT06456606
Status:
COMPLETED
Last Update Posted:
2024-06-13
First Post:
2024-05-31
Brief Title:
Cardiopulmonary Effects of Prone Position in CARDS
Sponsor:
Bakirkoy Dr Sadi Konuk Research and Training Hospital
Organization:
Bakirkoy Dr Sadi Konuk Research and Training Hospital
Study Overview
Official Title:
The Effect of Prone Position on Right Ventricular Functions in CARDS is Survival Predictable When Evaluated Through Transesophageal Echocardiography
Status:
COMPLETED
Status Verified Date:
2024-06
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
In coronavirus disease-2019 COVID-19-related ARDS C-ARDS especially in the severe form increased shunt rate impaired ventilationperfusion ratio VQ hypoxic pulmonary vasoconstriction inhibition and increased immune microthrombosis may have similar effects on the right ventricle The cardiopulmonary pathophysiology and outcomes of C-ARDS vary and this variability requires monitoring to follow the diagnosis and treatment process This study aimed to increase the treatment success of the prone position in C-ARDS and to provide a prognostic factor for survival by analyzing and monitoring heart-lung interactions Therefore we used transesophageal echocardiography TEE to evaluate the cardiopulmonary effects of prone position
Detailed Description:
This prospective study included 30 moderate-to-severe C-ARDS patients who were treated with prone position in the first 48 hours of invasive mechanical ventilation support It was evaluated with transesophageal echocardiography three times before prone position PP T0 the first hour of PP T1 and the first hour of returning to the supine position T0 24 hours T2 after 23 hours prone position treatment Right ventricular end-diastolic arealeft ventricular end-diastolic area RVEDALVEDA was preferred right ventricular evaluations as primer outcome Static compliance C-stat was examined in the evaluation of the pulmonary effect of prone position as secondary outcome
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None