Ignite Creation Date:
2024-06-16 @ 11:51 AM
Last Modification Date:
2024-10-26 @ 3:31 PM
Study NCT ID:
NCT06450301
Status:
RECRUITING
Last Update Posted:
2024-06-11
First Post:
2024-05-28
Brief Title:
Senescent Endometrial Cells in Patients With Thin Endometrial Lining
Sponsor:
Trio Fertility
Organization:
Trio Fertility
Study Overview
Official Title:
Is Thin Endometrial Lining Associated With Senescent Endometrial Cells
Status:
RECRUITING
Status Verified Date:
2024-08
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
The goal of this observational study is to determine if thin endometrial lining that is unresponsive to estrogen might be associated with the presence of senescent cells in patients following long-term use of oral contraceptives The main question it aims to answer is
Are there any senescent cells present in thin endometrial lining
During the luteal phase of the cycle participants will will undergo
Gynecologic US to measure the endometrial lining thickness and pattern
Endometrial biopsy with Pipelle catheter
Are there any senescent cells present in thin endometrial lining
During the luteal phase of the cycle participants will will undergo
Gynecologic US to measure the endometrial lining thickness and pattern
Endometrial biopsy with Pipelle catheter
Detailed Description:
The investigators hypothesized that senescent cells in the endometrium may be the cause of the failure of thin endometrium to respond to normal growth stimuli such as estrogen
The outcome that research team anticipate to measure is the percentage of senescent cells in the endometrial biopsies of women with thin endometrium compared to the control group biopsies
The outcome that research team anticipate to measure is the percentage of senescent cells in the endometrial biopsies of women with thin endometrium compared to the control group biopsies
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None