Ignite Creation Date:
2024-06-16 @ 11:51 AM
Last Modification Date:
2024-10-26 @ 3:31 PM
Study NCT ID:
NCT06442579
Status:
RECRUITING
Last Update Posted:
2024-07-15
First Post:
2024-05-29
Brief Title:
The Influence of Cortical Lateralization on Selective Motor Control of the Arm Swing During Independent Walking After Stroke
Sponsor:
University Hospital Ghent
Organization:
University Hospital Ghent
Study Overview
Official Title:
The Influence of Cortical Lateralization on Selective Motor Control of the Arm Swing During Independent Walking After Stroke
Status:
RECRUITING
Status Verified Date:
2024-07
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
The upper limbs play an essential role for safe and efficient walking in healthy persons and persons post-stroke Nevertheless in current post-stroke gait rehabilitation research the upper limbs are barely targeted To address this gap my project aims to investigate the selective motor control of the upper limbs during walking and the contribution of the cortical activity to the arm swing in independent walkers after stroke
To gain insight in the direct effects of stroke on the arm swing the primary motor control of the arm swing will be evaluated by determining muscle synergies ie group of muscles working together as a task-specific functional unit Additionally the cortical activity EEG-analysis during walking of persons post-stroke will be compared to healthy controls and the relationship between stroke-induced changes in cortical activity and arm swing deviations will be assessed Furthermore I will evaluate whether improvements in cortical activity relate to improvements in primary motor control of the arm swing
This innovative project will be the first to investigate the direct coupling between the cortex and the muscle synergies in persons post-stroke during independent walking to investigate the arm swing These fundamental insights in the primary motor control of the arm swing and the contribution of the cortical activity will allow to develop targeted interventions aiming to improve arm swing and as such optimize post-stroke gait rehabilitation
Research questions
1 How can muscle synergies explain arm swing alterations in independent walkers after stroke
2 How do stroke-induced changes in cortical activity relate to arm swing deviations in persons after stroke
3 Are changes in primary motor control of the upper limb during walking related to normalization of brain activity in independent walkers after stroke
To gain insight in the direct effects of stroke on the arm swing the primary motor control of the arm swing will be evaluated by determining muscle synergies ie group of muscles working together as a task-specific functional unit Additionally the cortical activity EEG-analysis during walking of persons post-stroke will be compared to healthy controls and the relationship between stroke-induced changes in cortical activity and arm swing deviations will be assessed Furthermore I will evaluate whether improvements in cortical activity relate to improvements in primary motor control of the arm swing
This innovative project will be the first to investigate the direct coupling between the cortex and the muscle synergies in persons post-stroke during independent walking to investigate the arm swing These fundamental insights in the primary motor control of the arm swing and the contribution of the cortical activity will allow to develop targeted interventions aiming to improve arm swing and as such optimize post-stroke gait rehabilitation
Research questions
1 How can muscle synergies explain arm swing alterations in independent walkers after stroke
2 How do stroke-induced changes in cortical activity relate to arm swing deviations in persons after stroke
3 Are changes in primary motor control of the upper limb during walking related to normalization of brain activity in independent walkers after stroke
Detailed Description:
None
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None
Secondary IDs
| Secondary ID | Type | Domain | Link |
|---|---|---|---|
| 11PEU24N | OTHER_GRANT | FWO | None |