Ignite Creation Date:
2024-06-16 @ 11:51 AM
Last Modification Date:
2024-10-26 @ 3:31 PM
Study NCT ID:
NCT06442163
Status:
COMPLETED
Last Update Posted:
2024-06-04
First Post:
2024-05-18
Brief Title:
Average Volume-assured Pressure Support as Rescue Therapy in Obesity Hypoventilation Syndrome
Sponsor:
Assiut University
Organization:
Assiut University
Study Overview
Official Title:
Outcome Measures of Auto-titrating Average Volume-assured Pressure Support AVAPS as Rescue Therapy After CPAP Titration Failure in Patients With Obesity Hypoventilation Syndrome Adherence and Sleep Quality
Status:
COMPLETED
Status Verified Date:
2024-06
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
AVAPS
Brief Summary:
It remains unclear whether CPAP therapy should be prescribed if significant hypoxemia persists during CPAP titration despite optimization of upper airway obstructive events if maximum CPAP pressure is reached
The goal was to examine the effects of 6 months of home AVAPS therapy in patients with obesity hypoventilation syndrome as a potential option for patients who failed CPAP titration due to persistent hypoxemia
The goal was to examine the effects of 6 months of home AVAPS therapy in patients with obesity hypoventilation syndrome as a potential option for patients who failed CPAP titration due to persistent hypoxemia
Detailed Description:
Obesity hypoventilation syndrome OHS is one of the leading indications of home non-invasive ventilation NIV initiation In patients with OHS NIV improves daytime vigilance decreases PaCO2 improves sleep quality and improves physical activity
Thus the primary aim of this study was to evaluate the effects of 6-month noninvasive ventilation with average volume-assured pressure support AVAPS-AE ventilation on objective sleep quality and adherence to therapy in stable patients with OHS who failed CPAP titration
Thus the primary aim of this study was to evaluate the effects of 6-month noninvasive ventilation with average volume-assured pressure support AVAPS-AE ventilation on objective sleep quality and adherence to therapy in stable patients with OHS who failed CPAP titration
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None