Ignite Creation Date:
2024-06-16 @ 11:50 AM
Last Modification Date:
2024-10-26 @ 3:31 PM
Study NCT ID:
NCT06446479
Status:
RECRUITING
Last Update Posted:
2024-06-06
First Post:
2024-02-13
Brief Title:
Effects of THC on Alcohol Consumption and Neural Correlates of Reward
Sponsor:
University of Colorado Denver
Organization:
University of Colorado Denver
Study Overview
Official Title:
Effects of THC on Alcohol Consumption and Neural Correlates of Reward
Status:
RECRUITING
Status Verified Date:
2024-08
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
Alcohol and cannabis are often used together such that their effects overlap but little is known about the neural mechanisms that underlie simultaneous use High doses of THC have not been well-studied in the laboratory and it is unclear how high doses of THC may impact alcohol consumption patterns The proposed study will explore the effects of oral THC 20mg dronabinol vs placebo on neural reward alcohol self-administration and naturalistic co-use patterns
Detailed Description:
Participants will undergo a screening assessment baseline session and two laboratory visits The laboratory visits will involve an MRI scan and the opportunity to consume alcohol in our BAR lab Prior to the MRI participants will consume a placebo 0mg or high 20mg dose of oral THC dronabinol Visits will be separated by 7 to 14 days Dronabinol is an FDA-approved product that will be dispensed by our on-campus pharmacy
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
True
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
False
Is an FDA AA801 Violation?:
None