Ignite Creation Date:
2024-06-16 @ 11:50 AM
Last Modification Date:
2024-10-26 @ 3:31 PM
Study NCT ID:
NCT06448871
Status:
COMPLETED
Last Update Posted:
2024-06-07
First Post:
2024-05-02
Brief Title:
Ultrasound to Assess Sarcopenia in Prader Willi Syndrome
Sponsor:
Taipei Tzu Chi Hospital Buddhist Tzu Chi Medical Foundation
Organization:
Taipei Tzu Chi Hospital Buddhist Tzu Chi Medical Foundation
Study Overview
Official Title:
Usefulness of Ultrasound to Assess Sarcopenia in Individuals With Prader Willi Syndrome
Status:
COMPLETED
Status Verified Date:
2024-09
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
PWS
Brief Summary:
The aim of the study is to examine the clinical applicability of ultrasound as a diagnostic tool for sarcopenia in individuals with PWS by investigating the association between ultrasound-derived measurements DXA-derived measurements and sarcopenia-related outcomes
Detailed Description:
Sarcopenia is an age-related loss of muscle mass plus low muscle strength andor low physical performance that may affect over 25 of individuals over the age of 60 resulting in an increased likelihood of developing disability Abnormal body composition with an increased in body fat mass and a decreased in skeletal muscle mass were noted in individuals with Prader Willi syndrome PWS thought to be related to hormonal deficiencies due to hypothalamic dysfunction presenting as a unique congenital model of sarcopenia
Muscle mass can be measured by dual-energy X-ray absorptiometry DXA scan device but it is expensive increased radiation exposure and not easily accessible in all clinical practice Ultrasound USD is a non-invasive without ionising radiation low-cost and easily accessible tool for the assessment of soft tissue There were increasing evidence for the use of USD in the measurement of muscle thickness MT cross-sectional area CSA and pennate anle PA of different muscle groups in different populations However the use of USD as a routine diagnostic tool in individuals with PWS has not been reported yet
The aim of the study is to examine the clinical applicability of ultrasound as a diagnostic tool for sarcopenia in individuals with PWS by investigating the association between ultrasound-derived measurements DXA-derived measurements and sarcopenia-related outcomes
Muscle mass can be measured by dual-energy X-ray absorptiometry DXA scan device but it is expensive increased radiation exposure and not easily accessible in all clinical practice Ultrasound USD is a non-invasive without ionising radiation low-cost and easily accessible tool for the assessment of soft tissue There were increasing evidence for the use of USD in the measurement of muscle thickness MT cross-sectional area CSA and pennate anle PA of different muscle groups in different populations However the use of USD as a routine diagnostic tool in individuals with PWS has not been reported yet
The aim of the study is to examine the clinical applicability of ultrasound as a diagnostic tool for sarcopenia in individuals with PWS by investigating the association between ultrasound-derived measurements DXA-derived measurements and sarcopenia-related outcomes
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None