Ignite Creation Date:
2024-06-16 @ 11:50 AM
Last Modification Date:
2024-10-26 @ 3:31 PM
Study NCT ID:
NCT06449131
Status:
COMPLETED
Last Update Posted:
2024-06-07
First Post:
2024-05-12
Brief Title:
Persistent Pleural Effusion Treatment Following Cardiothoracic Surgery by Platelet-Fibrin Glue
Sponsor:
Daryoush Hamidi Alamdari PhD
Organization:
Mashhad University of Medical Sciences
Study Overview
Official Title:
Persistent Pleural Effusion Treatment Following Cardiothoracic Surgery by Platelet-Fibrin Glue A Clinical Trail
Status:
COMPLETED
Status Verified Date:
2024-06
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
Persistent pleural effusion is a life-threatening complication after cardiac surgery The traditional treatment is chest tube drainage which may not respond to treatment This study introduces a new noninvasive approach for treating persistent pleural effusion using platelet-rich plasma fibrin glue PRP-FG This method has been successfully applied for the treatment of postoperative persistent chylothorax and pneumothorax in previous studies which significantly decreased morbidity mortality and hospital stay
Detailed Description:
This pilot clinical trial recruited 19 patients at Imam Reza Hospital in Mashhad Iran 2023 who had developed unilateral or bilateral refractory postoperative effusion resistant to conventional thoracostomy treatment Treatment success was defined as effusion 50 mlday after 48 hours along with symptomatic improvement and no adverse events
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None