Ignite Creation Date:
2024-06-16 @ 11:50 AM
Last Modification Date:
2024-10-26 @ 3:31 PM
Study NCT ID:
NCT06447857
Status:
COMPLETED
Last Update Posted:
2024-06-07
First Post:
2024-05-31
Brief Title:
Extracellular Volume Associated With New-Onset Atrial Fibrillation
Sponsor:
The Affiliated Hospital of Xuzhou Medical University
Organization:
The Affiliated Hospital of Xuzhou Medical University
Study Overview
Official Title:
Cardiac MRI Extracellular Volume Associated With New-Onset Atrial Fibrillation in Patients With ST-Segment Elevation Myocardial Infarction
Status:
COMPLETED
Status Verified Date:
2024-05
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
Left ventricular fibrosis is strongly associated with atrial fibrillation AF However the relationship between LV fibrosis and new-onset AF NOAF after ST-segment elevation myocardial infarction STEMI is currently unknown This study was to investigate the relationship between different regions of ECV and NOAF during the acute phase of STEMI ECV in integral integral ECV non-myocardial infarction region NMI-ECV and myocardial infarction region MI-ECV was obtained by CMR
Detailed Description:
This retrospective study included patients diagnosed with STEMI at the Affiliated Hospital of Xuzhou Medical University All patients underwent CMR during hospitalization which included T1 mapping sequences The blood sampling was collected within 24 hours of the CMR examination Inclusion criteria 1 Successful pPCI TIMI flow 2 within 12 hours after symptom onset 2 Admission to the cardiac care unit for continuous electrocardiogram ECG monitoring after pPCI Exclusion criteria 1 Poor image quality 2 History of myocardial infarction 3 History of atrial fibrillation 4 Malignancy or inflammatory disease 5 Severe valvular heart disease 6 Thyroid dysfunction NOAF was defined as post-admission atrial fibrillation without a history of atrial fibrillation ECG monitoring revealed a suspicious rhythm during admission and an immediate 12-lead ECG confirmed NOAF Infarct-related arteries IRA were recorded based on CAG findings ECV in integral integral ECV non-myocardial infarction region NMI-ECV and myocardial infarction region MI-ECV was obtained by CMR
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None