Ignite Creation Date:
2024-06-16 @ 11:50 AM
Last Modification Date:
2024-10-26 @ 3:31 PM
Study NCT ID:
NCT06443268
Status:
RECRUITING
Last Update Posted:
2024-06-05
First Post:
2024-05-04
Brief Title:
Cerebrovascular Disease Quality of Life CODE QoL
Sponsor:
University of Zurich
Organization:
University of Zurich
Study Overview
Official Title:
Cerebrovascular Disease Quality of Life CODE QoL
Status:
RECRUITING
Status Verified Date:
2024-05
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
CODEQoL
Brief Summary:
The goal of this observational study is to learn about quality of life stress and caregiver burden in patients with stroke and their caregivers
The main question is
to discover the factors associated with quality of life and stress in patient-caregiver dyads
Participants will be asked to fill out questionnaires and agree to provide a hair sample in order to measure stress hormones in hair and consent to use of their routine clinical and laboratory data
Researchers will compare a group of participants without stroke to establish a comparable baseline
The main question is
to discover the factors associated with quality of life and stress in patient-caregiver dyads
Participants will be asked to fill out questionnaires and agree to provide a hair sample in order to measure stress hormones in hair and consent to use of their routine clinical and laboratory data
Researchers will compare a group of participants without stroke to establish a comparable baseline
Detailed Description:
IntroductionBackground
In Switzerland approximately 21000 people suffer a stroke each year Stroke causes neurological impairments for those affected and brings about a sudden change in their life situation The relatives of stroke patients receive new social roles and are challenged in a new way by the morbidity of the affected person leading to a change in their quality of life and aggravation of stress Unlike chronic diseases a stroke occurs suddenly so relatives have no opportunity to gradually adapt to the new living circumstances or to deal with the new psychosocial roles and demands beforehand To what extent the daily life of patients and their relatives changes and what impact this has on their quality of life and stress has not been systematically investigated in Switzerland thus far
Aims and significance of the project
The aim of the project is to systematically assess the quality of life and stress as well as to capture stress biomarkers in stroke patients and their relatives The investigators plan to conduct sequential measurements of quality of life and stress hormones at multiple time points over 12 months The goal is in particular to uncover the relationships between the extent of patients impairments their quality of life and stress in affected individuals and their relatives This is a first-time project with the goal of learning more about stressors and biological relationships This will create the basis for a multimodal intervention to improve the quality of life of those affected and their relatives which will be investigated in a follow-up project
Methods
The Investigators plan a prospective study with a survey of stroke patients and their relatives regarding their quality of life in everyday life It will also be examined how multiple stress biomarkers which will be determined in blood and hair are related to quality of life and stress and which clinical factors have a positive and negative influence on the well-being of patients and their relatives
In Switzerland approximately 21000 people suffer a stroke each year Stroke causes neurological impairments for those affected and brings about a sudden change in their life situation The relatives of stroke patients receive new social roles and are challenged in a new way by the morbidity of the affected person leading to a change in their quality of life and aggravation of stress Unlike chronic diseases a stroke occurs suddenly so relatives have no opportunity to gradually adapt to the new living circumstances or to deal with the new psychosocial roles and demands beforehand To what extent the daily life of patients and their relatives changes and what impact this has on their quality of life and stress has not been systematically investigated in Switzerland thus far
Aims and significance of the project
The aim of the project is to systematically assess the quality of life and stress as well as to capture stress biomarkers in stroke patients and their relatives The investigators plan to conduct sequential measurements of quality of life and stress hormones at multiple time points over 12 months The goal is in particular to uncover the relationships between the extent of patients impairments their quality of life and stress in affected individuals and their relatives This is a first-time project with the goal of learning more about stressors and biological relationships This will create the basis for a multimodal intervention to improve the quality of life of those affected and their relatives which will be investigated in a follow-up project
Methods
The Investigators plan a prospective study with a survey of stroke patients and their relatives regarding their quality of life in everyday life It will also be examined how multiple stress biomarkers which will be determined in blood and hair are related to quality of life and stress and which clinical factors have a positive and negative influence on the well-being of patients and their relatives
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None