Ignite Creation Date:
2024-06-16 @ 11:50 AM
Last Modification Date:
2024-10-26 @ 3:31 PM
Study NCT ID:
NCT06440096
Status:
COMPLETED
Last Update Posted:
2024-06-03
First Post:
2024-05-28
Brief Title:
Complete Blood Count-derived Indexes in Inflammatory Modic Changes
Sponsor:
Veysel Delen MD
Organization:
Sanliurfa Mehmet Akif Inan Education and Research Hospital
Study Overview
Official Title:
Harran University Hospital Department of Physical Medicine and Rehabilitation
Status:
COMPLETED
Status Verified Date:
2024-05
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
Some indicators generated from hemogram such as neutrophillymphocyte NLR have been suggested as biomarkers of systemic inflammation Type I Modic changes MCs have inflammatory nature histologically and are more painful clinically than type II MCs Therefore we hypothesized that patients with type I MCs may have increased inflammatory biomarkers and low back pain than those with type II MCs The aim of this study was to test this hypothesis
Detailed Description:
Patients and Methods A total of 48 patients with MCs type Itype II2424 were included in this study Their demographic clinical and hematologic characteristics were recorded A 10 cm Visual Analog Scale VAS was used to detect low back pain intensity Systemic inflammatory biomarkers including NLR monocytelymphocyte MLR plateletlymphocyte PLR neutrophillymphocyteplatelet NLPR systemic inflammatory index SII systemic inflammatory response index SIRI and aggregate index of systemic inflammation AISI were derived from whole blood cell count
Keywords Neutrophil-to-lymphocyte ratio inflammation Modic changes back pain
Keywords Neutrophil-to-lymphocyte ratio inflammation Modic changes back pain
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None