Ignite Creation Date:
2024-06-16 @ 11:50 AM
Last Modification Date:
2024-10-26 @ 3:31 PM
Study NCT ID:
NCT06441721
Status:
NOT_YET_RECRUITING
Last Update Posted:
2024-06-06
First Post:
2024-05-29
Brief Title:
Vitamin B12 Status and Its Impact on Chronic Haemodialysis Patient
Sponsor:
Assiut University
Organization:
Assiut University
Study Overview
Official Title:
Vitamin b12 Deficency and Its Impact on Chronic Haemodialysis Patient and Its Effect on Anemia and Neuropathy
Status:
NOT_YET_RECRUITING
Status Verified Date:
2024-05
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
Haemodialysis
Brief Summary:
To evaluate vitamin B12 level in haemodialysis patients and its impact on hematological and neurological manifestations
Detailed Description:
Vitamin B12 cobalamin is a water-soluble vitamin involved in several normal cellular functions 1 Vitamin B12 is required for the development myelination and function of the central nervous system healthy red blood cell formation and DNA synthesis 2- 4 Low levels of vitamin B12 have been associated with high concentrations of homocysteine Hcy and can lead to health complications 5 Hyperhomocysteinemia is an important risk factor for cardiovascular disease 6 Vitamin B12 and other B vitamins are involved in homocysteine metabolism and researchers have hypothesized that supplementation with these micronutrients can reduce the risk of cardiovascular disease by lowering homocysteine levels 7 8 Vitamin B12 deficiency is one of the causes of Macrocytic anaemia with increased mean corpuscular volume MCV defined as more than 100 fL which is the hallmark of megaloblastic anaemia
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None